microcephalous new-horn pig, etc. 
455 
At the same time, no pathological change marks such parts of 
the central nervous system as remain, so that this case does not 
fall into either class recognised by Giacomini in his study of 
human microcephali ( v . the comments thereon by Cunningham 
and Telford Smith, Sc. Trans. Roy. Dublin Soc. Vol. v, Series n, 
pp. 289, 290, 338). It forms a good contrast in this respect with 
the case of microcephalus in the human subject (Cambridge 
Dissecting Room, 1905) described in the sequel ( Proc . Qavib. 
Phil. Soc. Vol. xiv, p. 478), wherein the cord was affected as well 
as the cerebrum. 
Whether the perforation of the bucco-pharyngeal membrane is 
causally associated in normal cases with the great downward 
flexure of the anterior end of the brain with which it is con- 
temporaneous, I am not able to state definitely, but that the 
connexion may be of this sort is a reflexion suggested by this 
specimen. 
Cases of this kind are not unknown in domestic animals and 
are perhaps especially frequent in litters of pigs. The Hunterian 
Museum contains several comparable examples and with a note 
on these, this account will be brought to a close. 
The specimens in the Hunterian Museum form part of the 
Teratological series, and are numbered as follows : — A 210, 
A 210a, Nos. 274, 275, 276, 280, 281, 282, 284—287 inclusive. 
On these specimens I made the following notes. 
A 210 and A 210a. This is a human foetus. The conditions 
are almost exactly similar to those in the microcephalous pig here 
described. The bulb and pons were present, but no cerebellum 
or cerebrum. The third pair of nerves was thought to be present 
(cf. Catalogue). There is no note as to whether eyes were present 
or not. 
No. 274. This is a young pig, and the conditions are very 
similar to those described above. Part of the cerebellum and 
possibly part of the cerebrum are present : the walls of the 
auditory capsules are of porcelain-like appearance (as in the 
Cambridge specimen), and closely approximated. The cranial 
cavity is rather larger than in the Cambridge specimen, otherwise 
the dimensions of the two are similar. 
No. 275. Cranium of a young pig: general characters similar 
to those of No. 274 and of the Cambridge specimen. 
No. 276. Cranium of a kitten : similar to No. 274. 
No. 277. Cranium of a human foetus: similar to the fore- 
going, but probably some cerebrum was present. 
No. 278. Head of a foetal lamb: the cerebrum is cystic: 
there is a general similarity to the foregoing specimens. 
In these cases the tendency for the external ears to be united 
on the ventral aspect of the neck, is distinct (Otocephalus). 
