Pepper.] 20 [ Dec; 2, 
beginning in the face, and also, that in stooping, face felt puckered and 
wrinkled, while the effort to regain the erect position gave intense pain 
along the entire spinal column. Subsequently the fore-arms became sore 
and swollen, was placed under treatment, which was of such decided 
benefit that he thought himself entirely well, and in March, 1867, re- 
sumed his farm duties ; about two months later the symptoms returned 
in an aggravated degree, the feet and then, in succession, the legs and 
thighs becoming enlarged and very painful ; under the influence of con- 
stant bandaging the swelling diminished ; his appetite became impaired, 
and he died from exhaustion Feb’y 8th, 1868. The treatment adopted 
was mostly of a tonic character. 
DESCRIPTION OF THE SPECIMEN 
(See Plates I. and II.) 
I. WHAT BONES ARE WANTING. 
We have the entire skeleton except the following bones : 
Vertebra—dth and 7th cervical. 
1st and 10th dorsal. 
2d lumbar. 
2d and 4th sacral. 
all the coceygeal. 
Sternum, gladiolus and ensiform. 
Hyoid bone. 
Right Patella. 
Hands, all wanting 
g save the right seaphoid. 
Feet, all wanting save left calcis. 
Five metacarpal and metatarsal bones and eight phalanges are pre- 
served, but, except the two metatarsals of the great toe, they can scarcely 
be designated, they are so greatly deformed. 
II. THEIR CONDITION. 
Unfortunately, by the prolonged boiling to which they were sub- 
jected before coming into our possession, the bones have lost proba- 
bly all their animal matter, and are now almost as friable as if they had 
been burned. By removing the marrow, also, this has rendered the 
pathology of the disease much less clear and the microscopic examin- 
ation much less valuable than it would otherwise have been. Moreover, 
it has removed probably all the gelatine, so that the chemical examina- 
tion and the specific gravity would be worthless. Even the weights are, 
by reason of this misfortune, only of slight value. All the epiphyses too, 
except the coracoid process of the scapula, are separated from the shafts or 
bodies, and in some bones even integral parts are separated, e. g. the sa- 
crum is divided into its component vertebre and the innominate bone 
into two pieces. Many of the epiphyses are preserved, as will be indi- 
cated in describing each bone. The epiphyses have attached to them in 
many places the dried gelatinous articular cartilages of a transparent 
