436 
PROF. B. T. LOWIN' E ON THE STRUCTURE AND 
cells exhibit an oblong nucleus surrounded by a clear area 
(PI. XXVIII. fig. 16). 
In females in which the ovary is still without ripe ova (fig. 17) 
there are no corpuscles in the cells, but nuclei in an active state 
of division. Each nucleolus or each group of nucleoli, two or even 
four (figs. 17 and 18, i), is surrounded by a clear area. In some 
there is a small speck of deeply stained chromatin close to the 
nucleolus (fig. 19). 
The epithelial cells (fig. 20, e ) consist of distinctly reticular proto- 
plasm and stain readily. The largest of the contained corpuscles 
measures 25 /x to 30 /j. in diameter. A fully formed corpuscle 
exhibits a clear outer zone (fig. 20, d), 4 /x in breadth, with a 
distinct radial striation. This clear outer zone closely surrounds 
a finely granular contents (e) which stains feebly, and lying in it, 
usually near one side of the corpuscle, a clear vesicular spot ( b ) 
5 yu in diameter, with a bright highly refringent spherule 25 /ji in 
its centre («). 
These corpuscles have, in point of fact, the closest possible 
resemblance to the germ-ova of other animals. 
The relation of these corpuscles to the nuclei of the containing 
cells must at present remain a matter of conjecture. It appears 
to me probable that one of the nuclei of the cells in the young 
gland, when there are two or more, develops the corpuscle whilst 
the others remain quiescent. The nuclei both of the young and 
mature cells staiu deeply, whilst the vesicle and highly refractive 
body in the corpuscle remain unstained. 
In several instances I have seen an appearance which leads me 
to believe that the corpuscles when mature are discharged from 
the cells in which they are developed into the lumen of the gland 
(fig. 20). Either empty spaces in the cells or a distinct fissure 
surrounding the corpuscle which lies close to the lumen of the 
gland are not uncommon. In some preparations the corpuscles, 
or some of them, have evidently fallen out in mounting the spe- 
cimen. 
On other occasions I have seen what appears to be a rupture 
of the clear external zone, and a protrusion of the contents of 
the corpuscle into the lumen of the gland. There is certainly a 
close similarity between the contents of these corpuscles and the 
material which fills the lumen of the gland. 
