138 The Philippine Journal of Science 1918 



hours after injection was negative for diplococci. Each of the animals 

 continued to be in good health. 



Believing that the organism was becoming more and more 

 attenuated, no further experiments were attempted. The failure 

 to produce the disease in monkeys is attributed to the low vir- 

 ulence of the particular strain with which we were dealing. 

 The clinical course of the disease in the patient lends itself to 

 this belief. 



The agglutination reactions obtained with the organism and 

 the patient's blood, the location of the diplococcus, its presence 

 within the polynuclear cells, its morphology, its staining prop- 

 erties, and its cultural characters, as herein outlined, all form a 

 chain of evidence which, even in the absence of successful 

 animal experiments, convinced us that it is identical with Dip- 

 lococcus intracelhdaris meningitidis Weichselbaum. 



While this article was in type the meningococcus was isolated 

 by Dr. R. W. Hammack, College of Medicine and Surgery, 

 University of the Philippines, at autopsy from a case of men- 

 ingitis occurring in a Filipino 26 years of age. The organism 

 fulfilled all of the cultural, morphological, and staining charac- 

 ters of Diplococcus intracelhdaris meningitidis. This is the only 

 case from which the meningococcus has been isolated in 2,371 

 autopsies performed at the College of Medicine and Surgery. 



