360 ^^^ Philippine Journal of Science 191: 



The third pair of fowls was given 60 grams of the calcium 

 rice mixture per day, and, when the food was unconsumed, was 

 fed the balance. The calcium lactate-chloride fowl gained rapidly 

 in weight from 1,170 to 1,295 grams on the twenty-first day of 

 the experiments ; then the weight dropped slightly, and again rose 

 to 1,260 grams on the thirty-second day of the experiment, when 

 neuritis developed. Examination of the sciatic nerve showed 

 moderate although typical degeneration. The calcium chloride 

 fowl of this pair gained in weight from 1,167 to 1,300 grams 

 for the first two weeks, and then gradually lost weight, seemed 

 sick on the twenty-first day of the experiment, and died on the 

 twenty-fifth day. Neuritis symptoms were questionable, and the 

 sciatic fibers showed but little degeneration. It is probable that 

 these two fowls received too much calcium, in as much as they 

 were forced to consume almost twice the food per diem as was 

 eaten by the other two pairs after the first few days of the 

 experiment ; there was, however, no evidence of haemorrhages into 

 the tissues of the oesophagus between the crop and the muscular 

 stomach or of ulceration of the mucosa of the latter, which I 

 have observed in chronic calcium poisoning in some feeding 

 experiments not reported in this paper. 



Two fowls were given one-half the amount of lactic acid fed 

 in the above experiments, but in the form of sodium lactate. 

 One fowl gained rapidly in weight from 1,055 to 1,200 grams 

 on the twentieth day of the experiment, often voluntarily eating 

 75 grams of rice per day. The body weight did not fall below 

 1,150 grams until the thirty-seventh day of the experiment, when 

 he ate little and seemed sick. The salt mixture was changed 

 so that the fowl received twice the former amount of lactic acid, 

 half as sodium and half as the calcium lactate, and half the 

 amount of calcium chloride as was received by the calcium lactate- 

 chloride chickens in the above experiments. He was given, or 

 fed in part, 60 grams of this rice and salt mixture per day, and 

 rapidly improved in weight and condition. On the sixtieth day, 

 when the fowl weighed 1,187 grams, incipient neuritis was 

 evident. The fowl was killed on the sixty-second day. Examina- 

 tion of the sciatic nerve showed most profound degeneration, 

 nearly every fiber being involved. Numerous nuclei of the 

 embryonic nerve fiber type were found in histological prepara- 

 tions of the sciatic. The second sodium lactate fowl was started 

 simultaneously with the other, and rapidly gained from 1,040 to 

 1,160 grams the first week. Subsequently, he ate much less, and 

 the body weight dropped to 1,047 grams on the twenty-first day. 



