vm, n, « Schobl: Plague in Manila in 1912 423 



cells showed vacuoles. Small foci, most numerous under Glisson's capsule, 

 were scattered throughout the organ; they varied in size, but were not 

 larger than a miliary tubercle. The small necrotic foci were found to 

 consist of few necrotic liver cells. The center of the larger foci was fonned 

 by degenerated and necrotic liver tissue, surrounded by round-cell infil- 

 tration. Polymorphonuclears were also found in the zone of cellular 

 infiltration. There was a slight degree of hasmorrhage in each focus. 

 Epitheloid cells and large vesicular cells with several nuclei were to be 

 found. The foci, mentioned above, were sharply demarcated from the 

 surrounding liver tissue, which appeared to be intact. 



Spleen. — The structure was well preserved, the capsule thin. The 

 Malpighian bodies were normal as to the elements of which they consist. 

 Cells with pycnotic nuclei were scattered throughout the organ, and vesi- 

 cular cells with small, deeply stained, excentrically located nuclei were 

 present. Polymorphonuclears were found in the tissue in considerable 

 numbers. No localized necrotic foci could be found in sections through the 

 spleen. 



Cervical glands. — The blood vessels were considerably distended. A few 

 haemorrhages and polymorphonuclears were present. CEdema of the cap- 

 sules and suiTOunding tissue existed. Part of the gland was necrotic. 



Lungs. — The blood vessels were distended. The alveoli contained homo- 

 geneous masses and blood. There were numeious subpleural haemorrhages. 

 The bronchi were collapsed, and contained mucus. 



Kidneys. — The cortical part showed subdued structure; the epithelial cells 

 had an indefinite outline and occasionally showed vacuolization. The 

 modular part was better presei-ved. There were miliary subcapsular haemor- 

 rhages. A few small foci were scattered throughout both medular and 

 cortical parts. They consisted of round-cell infiltration. 



NATURAL PLAGUE INFECTION IN A CAT 



The experiments of the German Plague Commission proved 

 that cats showed considerable resistance to plague infection as 

 cutaneous and subcutaneous inoculations failed to infect them. 

 According to the Austrian Commission, cats develop submaxil- 

 lary buboes if fed on plague material. They are said by Albrecht 

 and Gohn " sometimes to recover. Out of four cats fed on 

 plague material two died of plague, one showing submaxillary 

 the other mesenterial buboes. Virulent plague bacilli were found 

 in the discharge from the nose and also in the fseces of cats 

 which apparently did not become infected after having been fed 

 on plague material. 



One case of spontaneous plague infection of a cat was recorded 

 by Thompson ^^ in Sydney. 



W. Hunter ^^ in Hongkong made observations on cats suffer- 



' t)ber die Beulenpest in Bombay im Jahre 1897. (1897), II B, II C. 

 '" Report of an outbreak in Sydney, 1900. Referred to in Kolle and 

 Wassermann (1903), 2, 510. 

 ''Lancet (1905), I, 1064. 



