906 - SOCIÉTÉ DE BIOLOGIE 



The solution is made as follows : 250 gr. of gum acacia, " extra 

 sélect ", ia pearl form (Gum Arabie U.S. P.), are ground up and dis- 

 solved in 720 c. c. hot water. Constant stiring is necessary to prevent 

 the gumming of the acacia into a very slowly dissolving mass. To 

 this solution 180 gr. of pure glucose are added. The whole will amount 

 to about 1000 ce. It is filtered under pressure through a thick pad of 

 glass wool and fîUed into centrifuge bottles, which then are plugged 

 with cotton wool, sterilizedat a température of 100°, for 30 minutes on 

 three successive days, and then covered with rubber caps. A very 

 slight flocculet precipitate may form during stetilization, and also on 

 standing suhsequently. This is so slight that it is apt lo escape détec- 

 tion, and must, therefore, be carefuliy looked for. H it forms, it can 

 be removed, besl just before the solution is used, by centrifuging for 

 an hour. 



The dose, basei upon considérations oullined in previous reports, 

 bas been 5 c. c. per kil. of body weight. Tliis dose is given in the 

 course of 1 hour, so as not lo exceed Ihe just tolérant raie of glucose 

 administration, namely 0,9 gr. per kil. of body weight an hour (Wood- 

 yalt). Whelher or not more rapid injection would give less favorable 

 resulls \ve are not in a position lo state. 



Table 1 (similar to Tables 1, 2, 3, and 4 of our former report) gives 

 Ihe essentiel détails of the acceptable cases (lliat is of thé cases left 

 after excluding cases of maiked abdominal liemorrhage, and cases in 

 which Ihe arterial pressure began to fall before the two hoursperiod of 

 observation had elapsed). There in jncluded in this Table a case 

 (N» 215) which we hâve not accepted, allhough strictly it is not excluded 

 by our rules. The pressure in this case began to fall immediately 

 after the termination of the two hours period. This bas happened in 

 other cases which hâve been included in Ihe séries, but we feel justified 

 excluding Ihe présent case, because, in addition, the pressures never 

 got above 64 millim. Hg. a level which is miilim. below the lowest 

 observed in ail of our 168 cases. 



Table II, which is lo be fitled as the .o'''line into Table .j of our former 

 report, summarizes Ihe resulls. "When Ihe results are thus compared 

 with those previously obtained it becomes obvious that in every respect 

 save one the advanlage is decidely wilh the acacia glucose combina- 

 tion. Depeding upon Ihe method of considering Ihe data, the com- 

 bined injection saves from 28 to 40 cases of every hundred. 



But allhough the percentage of deaths is reduced by the treatmenl, 

 the number of animais that died within the first 24 hours (3) was larger 

 Ihan in the case either of the British Commiltee solution, or of the 

 successive injection of gum acacia ând glucose (1 each). This might be 

 taken lo mean either that the mixture in certain cases does harm or 

 that it fails lo save only those cases which in any event would quickly 



