SECRETION PHYSIOLOGY, 311 



c. The Augmentation of Sympathetic Saliva. 



That the small amount of sympathetic secretion, in the cases 

 just cited, is due to the presence of a small amount of fluid in 

 the ducts and alveoli is indicated by the abnormally large sym- 

 pathetic secretion, when the amount of liquid saliva in the gland 

 is rendered abnormally large by stimulation of the chorda, or by 

 the action of pilocarpine, nicotine and other drugs. 



Langley^^ first observed the augmentation of sympathetic 

 saliva by an immediately preceeding stimulation of the dilator 

 nerve in the dog's parotid and submaxillary and the cat's sub- 

 maxillary. The following experiments confirming Langley illus- 

 trates this augmentation. 



Experiment. VII. 



Dog under morphine and chloroform, sympathetic and chorda 

 cut. Canula in Wharton's duct. Secretion in mm. is given 

 above the line for every lo seconds, 250 mm. =0.82 cc. 

 Below the line is indicated the nerve stimulated ; s, is the sym- 

 pathetic ; c, the chorda. If no letter is written, it indicates that 

 at these intervals there was no stimulation. 



10, 35, 31, 2, 25, 4, 3. 2, 2, 8, 6, 4, n, 2, 2, I, 2, I, 3, 





c sssss ssssss 





3, 4, i>^, iK' I' 2, I, 4, 4, I, I, I, I, I, 2. i>^, 3, I, I, 0, 5, I, I, 





sssss ssss sss sss 





y^, 0, Yi, y,, 8, 60, 38, 2, I, 15, 3, I, 3, 3> 2, 2, 3, 2, 4, I, I, 2, 2, I 





s cc ssss sss 





T T T /I r -70 ■-> V%\ --»/|'>').-»QtTT'> 





^, ^1 •"•> "■) ••> 4.^> S^i :>•) ^w, '-■> 4j ^> 31 ^j «», 1, i, i, ^5 





sss c ssss ssss c. c. c. 





18, 7, 3, 3, 2, y,, 4, 2. 2, y,, I, 30, 29, 4, 0, 0, 





ssssss sss Chorda i minute ssss 





4, 3, 2, 2, I, I, 3, etc., 





sssss 





It will be noticed, in this experiment, that the first secretion of 

 the sympathetic, immediately following the chorda stimulation, 

 is abnormally large, but that the augmentation effect rapidly 

 passes off The augmented saliva, as Langley pointed out, is 



