360 MATHEWS. 



can hardly be explained, I think, on the basis of secretory cell 

 activity. 



(2) Pilocarpine, which does not cause contraction of the mus- 

 cular sheath, causes a profuse secretion. 



(3) The vaso-motor and secretory fibres in the cat follow the 

 same paths. 



(4) Pilocarpine causes sweat secretions fourteen days after 

 nerve degeneration. 



(5) If the blood supply be cut off, on readmitting the blood 

 after 30 minutes, a spontaneous secretion occurrs.*^ The sim- 

 ilar secretion in the submaxillary is invariably accompanied by 

 vaso-dilation. 



(6) Increasing the capillary blood pressure or drinking large 

 quantities of water increases secretion. 



The facts, as far as they go, are the same as those observed 

 in the cerebral salivary secretions and pancreatic secretion 

 They justify us, I believe, in classing all three secretions in the 

 same category. That these sweat secretions are of an osmotic 

 character would thus be indicated. That other sweat secretions 

 are due to muscle there can be little doubt. 



/;. The Secretion of the Pancreas. 



Secretion of the pancreas is normally accompanied by vaso- 

 dilation. In its relation to atropine, its increased content of or- 

 ganic bodies coincident with an increased rate of flow, and in 

 taking place after compression of the aorta, pancreatic secretion 

 resembles the submaxillary secretion on stimulation of the 

 chorda tympani. There is reason to believe, however, that the 

 pancreas cannot secrete unless the blood vessels dilate. Thus 

 the means employed by Pawlow,'^'' Mett'^ and Kudrewetsky^^ to 

 give the vagi a secretory function are just the means used by 

 Bowditch, Luchsinger and others''*^ to give the sciatic and other 

 mixed dilator and constrictor nerves a dilator action. These 

 authors either cut the vagi and splanchnics, and allowed them to 

 degenerate three or four days, or else they stimulated them 

 with rythmic induction shocks, at the rate of one per second 

 after division of the cervical cord. There are two possible ex- 



