STREPTOTHRICOSIS. 457 



is', capixe: 



Monkey No. 385S was inoculated into the abdominal cavity with one loop of 

 a two weeks' culture and ten days later the animal was killed. Autopsy shows 

 numerous miliary, tubercle-like bodies on the mesentery, diaphragm, and on the 

 surface of the liver. There is slight adhesion of the omentum to the abdominal 

 wall at the site of the inoculation. 



Monkey No. 3625 was inoculated into the subcutaneous tissue and into the 

 peritoneal cavity with a suspension of this organism. The animal died three 

 weeks later. Autopsy shows extensive adhesions around the site of inoculation 

 and there is a large abcess in the abdominal wall. On section the abcess contains 

 a heavy, creamy, pus-like material in which are numerous, minute, grayish- 

 white granules. These granules are composed of microorganisms and a pure 

 culture is easily obtained by transplanting the granules to artificial media. 



Guinea pig No. 3859 was inoculated in a similar manner as were monkeys 

 numbered 3858 and 3625 and the lesions produced were similar to those described 

 for the monkeys. Intravenous inoculations of rabbits gave negative results in 

 the animals used. 



iS'. canis.: 



Monkeys numbered 3633 and 3626 were inoculated in the abdominal cavity 

 with one loop of a two weeks' culture and a two months' culture of this organism' 

 respectively, and both animals were killed two weeks later. Autopsy shows 

 slight adhesions near the site of inoculation. The omentum and mesentery are 

 intensely congested and contain numerous miliary, tubercle-like granules. 



Monkeys, guinea pigs, and rabbits inoculated subcutaneously showed no pro- 

 gressive lesions at autopsy. Intravenous inoculation of rabbits gave negative 

 results. Intraperitoneal inoculation of guinea pigs in two instances produced 

 lesions similar to those described for intraabdominal inoculations in monkeys. 



8. chalcea. 



Monkeys, guinea pigs, and rabbits when inoculated subcutaneously and intra- 

 peritoneally gave negative results. 



LITERATURE. 



A review of the literature of this subject may for convenience be divided 

 into two divisions (1) genus and (2) species determinations. 



Several of the generic names which have been introduced are clearly 

 descriptive of organisms belonging to other genera such as Cladothrix or 

 Leptotlirix, and some refer to organisms properly belonging to the classes 

 O'idia or Bacteria. 



GENUS. 



The generic names which appear to have some claim for consideration 

 are as follows : 



STREPTOTHRIX. 



Corda named this genus, giving, according to Saccardo (Sylloge Fungorum 

 (1886), 4, 282) the following generic diagnosis: 



"Hyphse fertiles erectaa, virgato-ramosas, ramis ramulisque spiraliter tortis. 

 Conidia globosa v. ovoidea, in ramulis solitarie acrogena, subinde pleurogena, 

 sessilia v. stipitellata, fusca." 



Cohn ( Untersuchungen iiber Bacterien, II. — Beitriige zur Biologie der Pflanzen 

 (1875), 1, 186) used the name Streptothrix in a new sense in describing an 



