STREPTOTHRICOSIS. 467 



James Homer Wright (Journ. Med. Research (1904), 13, 341) ) cultivated what 

 he believes to be a single species of Actinomyces from 13 cases of human actinomy- 

 cosis and two cases of the bovine disease. He considers his organism to be of the 

 same species, if not identical, with that of Wolff and Israel. This article is the most 

 thorough study of one species of this group of organisms that has yet been made. 

 Stokes {Am. Journ. Med. Sci. (1904), n. s. 128, 861) obtained a Streptothrix 

 from an abscess of the lung. This organism was acid-fast, grew aerobically and 

 was pathogenic for laboratory animals. Sehabad {Ztschr. f. Byg. (1904), 47, 41) 

 considers the true Actinomyces and the organisms of Bostroem or Eppinger to be 

 different species. .He cultivated from the sputum and abscess of the breast in one 

 human case an organism which he considered to be identical with that of Eppinger 

 in its morphology, biology, and pathogenicitj 7 . Hartman (Tr. Chicago Path. Soc. 

 (1904), 6, 157) cultivated a Streptothrix from one human case. The articles by 

 Tuttle {Med. and Surg. Rep. Presbyterian Bosp. N. Y. (1904), 6, 147) and Mc- 

 Donald {Scot. Med. & Surg. Journ. (1904), 14, 305) are not available to us. 



Pinoy (Comp. rend. acad. sci. (1906), 143, 1175) isolated a Streptothrix and 

 claimed to have experimentally reproduced the black granules by inoculation of 

 cultures into a pigeon's foot. His organism was a facultative anaerobe. Nicolle 

 and Pinoy {Arch. d. parasitol. (1906), 10, 437) cultivated a Streptothrix from 

 a case of mycetoma in an Arab. 



Musgrave and Clegg {This Jumal, Sec. B. (1907), 2, 477) obtained a culture 

 from the sinuses in a case of the ochroid variety of mycetoma occurring in a Filipino 

 woman in Manila. The cultural characteristics have already been described and 

 will be further discussed. Poppenheimer and Satchwell {Journ. Infect. Dis. 

 (1907), 4, 617) report a case of endocarditis and isolation of a pleomorphic bac- 

 terium resembling somewhat closely the Streptothricce. They review the literature 

 of Streptothrix infections in man and tentatively classify their organism as a 

 Gladothrix. The report of these authors is thorough and complete and from their 

 description it does not seem as if their organism could properly be considered under 

 Streptothricce. 



Strong cultivated a Streptothrix from a case of mycetoma in India. This 

 organism is undoubtedly identical with that of Vincent. 



OTHER STREPTOTHRICCE. 



In addition to the pathogenic organisms of the group under discussion and 

 which have been isolated from pathologic lesions in man and animals, others have 

 been cultivated from sputum, pus, or other human excreta under circumstances 

 which make their exact source questionable; there are still others which have 

 only been described as being obtained from animals ; and some have been cultivated 

 only from air, water, soil, and other outside sources. The following may be men- 

 tioned: S. rubra of Ruiz-Casab6 (ref. Centralbl. f. Bakt., etc. (1895), 17, 466) 

 isolated from sputum; Cladothrix mordore of Thiry {Arch. d. physiol. (1897), 

 29, 284) obtained from an anginal exudate; the Streptothrix of Dean {Tr. Path. 

 Soc. (1900), 51, 26) isolated from an abscess of the jaw in a horse; and S. lacertce 

 of Terni (ref. Centralbl. f. Bakt. etc. (1896), 19, 953) isolated from nodules in 

 the liver of a lizard. Rossi-Doria {Ami. d. I'Ist. d'ig. sper. d. Univ. di Roma 

 { 1891 ) , 1 ) cultivated a Streptothrix from a case of bovine actinomycosis. Sanfelice 

 ( Centralbl. f. Bakt. etc., orig. { 1904) , 36, 355 ; and Arch. f. wiss. u. prakt. Thierheil t 

 (1896), 22, 153) obtained Streptothricw from several minor cases of bovine 

 actinomycosis. He considered his organisms to be similar to those of Gasperini 

 and Doria. Gasperini {Proe.-verb. Soe. Tose. di Sci. Nat. (1895), 9, 64; 292) 

 isolated and described two strains of Streptothrix from actinomycosis in cattle. 

 He {Ann. d. I'Ist. d'ig. sper. d. Univ. di Roma (1892), 2, 167; Proc.-verb. Soc. 



