468 MUSGRAVE, CLEGG, AND POLK. 



Tosc. de. Sci. Nat., July 5, (1896) also worked with a number of cultures obtained 

 from other authors including that of Dessy {loc. cit.). With this latter organism, 

 he stated that he had produced typical actinomycosis by injection into the jaw 

 of a cow. 



Lange and Man'asse (ref. Levy. Gentralbl. f. Bakt. etc. 1,1899), 25, 5) isolated 

 a Streptothrix somewhat resembling that of Wolff and Israel from actinomycosis 

 in a dog. Bahr {Ztsclir. f. TMermed. (1904), n. s. 8, 47) cultivated a Streptothrix 

 from an actinomycosis-like disease in a dog. Dean (Tr. Jenner Inst. Prevent. 

 Med. (1899), 2, 17) did the same with an organism resembling that of Wolff and 

 Israel, obtained from an abscess in the jaw of a horse and this Streptothrix was 

 pathogenic for animals. Mosselmann and Lienaux (Ann. d. ined. vet. (1S90), 

 39, 409) obtained a Streptothrix from a case of bovine actinomycosis. 



Lignieres and Spitz (Bull. Soc. centr. d. med. vet., Paris (1902), 56, 487) 

 cultivated a bacillus from cases of clinical actinomycosis in cattle. They state 

 they produced true actinomycosis, the organism showing the club-shaped Strep- 

 tothrix granules, with cultures of this organism, by inoculation of their cultures 

 into cattle. 



The Streptothrix of Caminiti (Gentralbl. f. Bakt. etc.. oriy. (1907), 44, 193) 

 is one of the most important of the organisms cultivated from the air, because of 

 its pathogenic properties and close cultural resemblances to the Streptothricce 

 which produce clinical actinomycosis. This organism is Gram positive, acid-fast 

 in part, a facultative aerobe with anaerobic preferences, liquefies gelatin and 

 produces pigment in varying amount and color in artificial media. It is pathogenic 

 for all animals experimented upon, producing circumscribed local lesions by in- 

 jection of cultures. 



Other organisms of this class which may be mentioned are /S. leucea Foulerton 

 (Tr. Path. Soc. (1902), 53, 101) isolated from sewage and water; S. alpha Jones 

 (ibid, 102); <S'. erythrea Foulerton (Ibid, 107) from culture tubes prepared with 

 horse serum; 8. beta Jones ( ibid, 109) ; Cladothrix invulnerabilis of Acosta and 

 Grande Rossi (ref. Gentralbl. f. Bakt, etc. (1893), 14, 14); the Streptothrix of 

 Kedzior (Arch. f. Hyy. (1S90), 27, 328) isolated from sewage and water; S. 

 albido-flava, S. carnea, and »S'. aurantiaca of Rossi-Doria (Ann. d'Ist. d'iy. d. Roma 

 (1891), 1) isolated from air: Mieromyces hoffmanni described by Gruber (ref. 

 Gentralbl. f. Bakt., etc. (1891), 10, 648) isolated from air. 



Several other brief descriptions of Streptothricce from pathologic 

 lesions might be noticed, but the principal ones have been mentioned 

 above. The technical descriptions have for the greater part been omitted 

 in this review of the literature, but it may be stated that a classification 

 or this material which will be satisfactory to all is scarcely possible. 

 However, several authors have attemped an arrangement of species and 

 varieties. 



Foulerton worked with a large collection of cultures obtained from various 

 sources. He redescribed and renamed several species, both pathogenic and non- 

 pathogenic, the classification being based largely upon morphologic and cultural 

 characteristics. Rossi-Doria occupied himself for the greater part with Strep- 

 tothrica} cultivated from extraneous sources and his classification is based upon 

 the character of the cultures obtained. Gaspereni gave a classification based 

 upon cultural characteristics. Brumpt (Areh. d. parasitol. (1906), 10, 489) 

 recognized several species and more than one genus. Wright worked with one 

 species and gave the most complete description of that organism to be found in 

 literature. His "Hyphomycete" cultivated from a ease of the "black variety" 

 of mycetoma evidently was not a Streptothrix and therefore is not included in 



