The Structure of Colored Blood- Corpuscles. 271 



puscle is met with having a central, or slightly excentric, dot 

 of such relatively large size that it might be interpreted as a 

 nucleus (see No. 1 of fig. 5). 



Some movement takes place in the network ; for sometimes 

 the threads change in length, and perhaps in thickness, and 

 the dots change their position and their size. 1 



In the course of another half hour or hour, the network be- 

 comes less distinct in the palest corpuscles ; and in these grad- 

 ually fades away. Then, for some time, the network remains 

 visible in nearly all corpuscles except those that are too pale 

 or too small : vacuoles, one or more, appear in many of the 

 latter ; while the former occasionally show indications of 

 irregularly massed matter in their interior, though usually 

 nothing is seen of them but double-contoured rings which 

 have been called their " ghosts " (see fig. 6). During this 

 time, also, a quantity, sometimes rather large, of detritus 

 accumulates. 



It appears as though the network is most plain in corpus- 

 cles that have suffered either not at all, or but little, from de- 

 tachment of a portion of their substance. The active changes 

 of indentation and protrusion have usually disappeared in a 

 large number of corpuscles, by the time " paling " has suf- 

 ficiently progressed to render the interior structure visible. 

 As before stated, some corpuscles permanently retain scalloped 

 and knobbed forms, while the majority are finally more or 

 less rounded off; but the play of changing shape of many 

 corpuscles is going on at the same time that this network is seen. 



After a while, further " paling " stops, and the network 

 structure of all corpuscles which show it, remains visible indef- 

 initely long. 



Blood-corpuscles, from hemorrhage in the bladder, in the 



(1) To make sure of the occurrence or non-occurrence of this movement, I used the mic- 

 rometer scale, and having with great precaution as to entire rest of the microscope and the 

 specimen, fixated by lines the position of the dots and length of the threads, the changes of 

 position, size, and length became unmistakable. 



