The Structure of Colored Blood- Corpuscles. 275 



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red corpuscles, finely granulated and coarse granular, the 

 granules always being the points of intersection of the threads 

 of the network. In both kinds the body as well as the nucleus 

 exhibited the reticulum structure. The network of the body 

 and that of the nucleus were connected by fine threads pass- 

 ing through the nuclear envelope. In many instances the 

 body was reduced either to two polar flaps, bulging from each 

 side of the nucleus, or to one flap, more or less colored, at the 

 side of the nucleus; in other instances, it was uniformly con- 

 tracted around the enlarged nucleus. 



Many colored corpuscles contained vacuoles, in varying 

 number, which were either empty or traversed by an exceed- 

 ingly delicate, apparently stretched, reticulum, or else con- 

 tained irregular accumulations of matter with remnants of 

 the network. aa:*s=*, 



II. 



My observations as to amoeboid movements of colored blood- 

 corpuscles, as well as to varieties of size and shape, — observa- 

 tions which were really only incidental while investigating 

 the structure, the main object of my researches, — have been 

 anticipated by previous investigators. One saw and report- 

 ed as an extraordinary finding, one or more forms or active 

 form-changes like those I have described, another others ; 

 some a far greater number than I. " Fehlt leider nur das 

 geistige BandP The band which connects and explains the 

 phenomena observed is the discovery of the structural ar- 

 rangement. 



In the following historical sketch of points bearing on my 

 observations, I shall refer to a few only of the legion who 

 have made colored blood-corpuscles the subject of their in- 

 vestigation. 



More than a hundred years ago, William Hewson, after 

 asserting that the red corpuscles are of different sizes in dif- 

 ferent animals, added ; "I have likewise observed that they 



