The Structure of Colored Blood- Corpuscles. 307 



completely surrounds, while the membranous layer appears iso- 

 lated, manifesting itself by a double contour. And again, if the 

 same process should take place without entirely separating the 

 protoplasm from the membranous layer, but leaving at certain 

 small points a union between the two parts, the result must be 

 the production of a number of filamentary processes, arising 

 from the main bulk of the protoplasm, and passing to those 

 points of the membranous layer." 1 



Kneuttinger considered the two surfaces of the biconcave disk 

 of blood-corpuscles to be connected at the place of the depression 

 by protoplasma threads ; if these tear, the biscuit form changes 

 to a sphere. 2 



According to Krause, the red blood-corpuscle consists of — 1. A 

 colorless stroma formed by a solid albuminous matter arranged 

 into radial fibers, and — 2. Haemoglobin, which is a colored fluid 

 albuminous matter lying in the interspaces of these fibers. 3 



Lieberkilhn has found that the free nuclei of red blood-cor- 

 puscles of salamandra and tritons (the blood having been kept 

 for some time in colored glass tubes) consists of two substances, 

 of which one forms the envelope and septa or threads passing 

 more or less regularly through the interior ; the other being con- 

 tained between these septa. 4 



In the nuclei of colored blood-corpuscles Butsclili, W. Flein- 

 ming and Klein have reported the existence of a net-work, viz. : 



In the nuclei of red blood-corpuscles of frog and newt, But- 

 sclili observed fibrils, with granular thickenings, traversing the 

 nucleus and passing to and connecting with its envelope. 8 



Flemming saw a very delicate and dense network of fibers per- 

 vading the interior of the nucleus, and attached to the nuclear 

 membrane in many so-called cellular elements of the bladder of 

 curarized salamandra maculata. He inferred that the net-work 



(1) Ibid. p. 106. 



(2) Zur Histologie des Blutes. Wurzburg, 1865, p. 22. 



(3) AUgemeiDe und Mikroskopische Anatomie, p. 325— 334. 



(4) Lnc. (At. 



(5) " Studien iiber die ersten Entvrickelungsvorgange der Eizelle, die Zelltheilung UDd die 

 Conjugation der Infusorien." Abhandlungen der Serjckenbergischen Naturforschenden Ge- 

 sellschaft, vol. X, Heft 3, 4 (1876), p. 260. 



