22 Th. Lewis, 



5. Large faintly granular cells stained with eosin, diameter 20 /i. 



6, Cells smaller than the preceeding with large pale nuclei oval or 

 crescentic in form." 



Variety 5. I have not observed, and the mnltinuclear cells have 

 been but very rarely seen in any of the glands, though frequently 

 met with them in sections of spleen. 



The sinuses}) In addition to the sinuses both peripheral and 

 central above described, other minor sinuses occur in the capsule itself. 

 These are small and narrow, and are most abundant in certain glands 

 with thick capsules. The sinuses contain the usual constituents of 

 the blood stream, and in addition phagocytes in all stages of activity. 



The eosinophile blood corpuscle has attracted as already stated 

 the special attention of Weidenreich ^) who believes that ordinary 

 leucocytes take up erythrocytes and partially disintegrate them, with 

 the formation of eosinophile granules. The leucocytes are then sup- 

 posed to join the general bloodstream, in which they form the well 

 known eosinophile cell. This striking and ingenious theory has se- 

 veral serious objections. In the first place it would be expected, by 

 analogy, that the action of leucocytes upon ingested blood cells would 

 be similar to that of phagocytes, and would not cease at the mere 

 setting free of hsemoglobin. Secondly, according to Kanthack and 

 Hardy [8], the application of suitable stimuli to such cells in the blood 

 stream, causes them to actively increase. How would this increase 

 of eosinophile corpuscles proceed, without the ingestion of further red 

 blood corpuscles, to compensate the loss of eosinophile particles in the 

 individual cells? 



The question as to the nature of reticulum and endothelium has 

 received considerable attention in lymphatic glands and spleen, but 

 has not yet been thoroughly worked out in haemal glands. In exami- 

 ning these elements, I have employed the methods now usually in 



') Drummond loc. cit. p. 203 makes the statement that in the larger hsmo- 

 lymph glands there are no blood corpuscles either in the central or peripheral 

 sinuses. If this be the case, by what right are they called "hœmolymph" glands 

 at all? 



^) Loc. cit. 



