The Structure and Functions of the hfemolymph Glands and Spleen. 35 



thy individuals are destroj^ed by the phagocyte ; and it is further j)Oò-- 

 sihle that the first stage in the disintegration may occur in the blood 

 stream. 



I now pass on to the further changes which occur in phagocytosis. 

 In liiMij giant cells j^ellow masses of pigment are observed, of the 

 dimensions of an erythrocyte, and moreover many intermediate forms 

 between the darJcIy stained spherical red bodies, and these masses of 

 pigment. Thus rounded masses are present which consist of two zones, 

 centrally of the dark highly refractive red, and peripherally of bright 

 yellow. The inner zone is irregular in outline, and the yellow zone 

 surrounding it has every appearance of eating its way into it (pi. I. 

 flg. 11 i.F)] between the two layers minute black granules are often 

 apparent, of the nature of which it is impossible to speak definitely, 

 though they are probably some intermediate form of pigment such as 

 hîçmatin. In some cases the yellow zone is increased at the expense 

 of the red, in other cases there is but a thin yellow zone surrounding 

 a larger red area; yet again there are yellow bodies with a tinge of 

 red spreading from the centre (pi. I. fig. 11 h.i). In all cases, when 

 present, the red zone is of the dark highly refractive red colour. 



Such bodies as have just been described, can only be regarded as 

 intermediate stages in the transformation of masses of hsemogiobin into 

 masses of pigment. 



Many observers have stated that pigment, in large quantities, is 

 found lying free in the blood sinuses of these glands, but I am unable 

 to confirm this statement. Only very small quantities have occasionally 

 been seen in a free state in this situation. The yellow pigment is 

 almost invariably enclosed in large amoeboid cells, while in the sinuses. 

 In some cases it is present in such quantities as to obscure the nucleus 

 (pi. I. fig. 11 / and pi. I. fig. 9 ph. 3): this may possibly account for 

 the view of previous observers that such pigment is free. 



It is very strikingly apparent in all my preparations that whereas 



the pigment in the cells of the sinus is usually finely granular, large 



quantities are found in the adenoid tissue in the neighbourhood of the 



sinuses Avhich is of a darker tint, often dark brown, consequent upon 



its collection into these larger masses (pi. I. fig. 8). In this situation 



3* 



