The influence of a meat diet on the kidneys. 207 



bread and milk miieli more of the N appears in tlie faeces, than with 

 liesh-feeding'. The nrinaiy N bears to the faecal X the following- 

 proportion in the three cases. 



A 16,3] 



B 15,8J ^''-^''^'- 



G 6,2 Bread and milk. 



The bulk of the faeces in the animal C was very much greater 

 than in the other tw^o. The same is trne of the volnme of urine 

 passed. This is seen from the following figures. 



A B C 



C. C. of urine 15 11 23 



Faecal pellets (number of) 24 12 52 



With a flesh-diet, therefore, the urine is more concentrated. 

 This was obvious from its high coloured appearance, as much as 

 from the relative^ small quantity passed. On bread and milk there 

 was much more diuresis, and the urine was notably paler in hue. 

 In no case were any abnormal constituents present. It was noticeable, 

 however, that in the meat-fed animals the urine had a much stronger 

 odour. As regards the faeces, they were ill-formed, scant}^, and very 

 dark with the meat-fed animals, but pale, bulky, and well-formed on 

 bread and milk. 



General conclusions. 



I. The prolonged administration of a flesh diet (horse-flesh and 

 ox-flesh) to rats is followed by hypertrophy of the kidneys. 



IL This hypertrophy is more pronounced in the second gene- 

 ration of meat-fed subjects. 



III. The horse-flesh diet induces in the great majority of ani- 

 mals definite histological changes which affect mainly the epithelial 

 structures of the kidney. These changes are similar to those seen 

 in recognised toxic conditions. 



IV. Similar changes of a less pronounced type are present in a 

 small proportion of the ox-flesh-fed subjects. 



V. In the kidneys of ox-flesh-fed animals which appear histo- 

 logically normal by ordinary staining methods, the application of 



