320 S. Simpson, 



ation 110 notice was taken when cold water was applied to tlie 

 right hand or foot, although when applied on the left side the limbs 

 were withdra^Mi at once. Water at 57^ C. was aways felt, but in 

 the case of the right foot only after a delay of 6 seconds. There 

 was no hemiopia. 



Secondary Degeneration. Coronal sections were made through 

 the thalamencephalon about the middle of the optic thalamus, but as 

 these had been imperfectly penetrated by the osmic acid, the amount 

 of degeneration in the internal capsule can not be properly estimated. 

 Thei'e is, however, mesial to the capsule, in the lateral part of the 

 grey matter of the thalamus very extensive fine degeneration. 



In the midbrain the left crusta contains degenerated fibres stud- 

 ded uniformly over its middle three-fifths, the lateral and mesial fifths 

 being practically free from degeneration. There is a slight amount of 

 fine degeneration in the substantia nigra of the same side. No fibres 

 are seen passing backwards from the left crusta into the tegmentum 

 either towards the anterior corpora quadrigemina or towards the cen- 

 tral grey matter. The cells of the 3^*^ nucleus are well seen on each 

 side but no fine degeneration is visible amongst them. 



Throughout the pons at the various levels, as in the cats and 

 dog examined, there is a large amount of fine degeneration scattered 

 around the pyramidal bundles on the left side; this is most marked 

 on their mesial aspect and is strictly limited to the left side, none being 

 visible across the middle line (figs. 9 and 10. pi. XVI). The bundles of 

 tlie pyramidal tract on the left side contain very thickly scattered 

 degenerated fibres, which however, are less abundant in the more 

 laterally placed bundles than in the rest. 



In the upper parts of the medulla oblongata a few fibres can be 

 seen coming off from the degenerated left pyramid and passing into 

 the formatio reticularis of the opposite and of the same side; these 

 are directed not backwards towards the grey matter occui)yiiig the 

 fioor of the 4^ii ventricle but more lateralwards as in the cat and 

 dog (fig. 11. pi. XVI). A few transversely cut fibres are seen on the 

 right si(l(^ near the base of the tubercle of Rolando. Sections through 

 the upper levels of the decussation show a few bundles of degenerated 



