204 



G. G. Heslop 



Serum 

 JNumber. 





Result of Comp 

 fixation test 



einent 



Result of P.M. examinations of the 

 animal supplying the test serum. 



88 



_ 





- > 





89 



- 





- ' 





90 

 91 



- 



Negative 





No lesions of CP.P. 



92 



- 





; 





•93 



- 



Negative 



- 



Tuberculosis in lungs and lymph glands. 

 No CP.P. 



'94 



- 



Positive 



- 



Active lesions of CP.P. in left lung, and 



95 







> 



fluid in chest cavity. 



96 



- 





. 





97 



- 





- 





98 

 99 



- 



Negative 



- 



.No lesions of CP.P. 



100 



- 





- 





101 



- 





- 





102 



- 





- < 





The positive reaction given by No. 53 is difficult to explain. 

 The lungs of this animal were submitted to a searching post- 

 mortem examination, but no lesions of contagious pleuro-pneu- 

 monia could be demonstrated in them. 



No. 52 was a calf two days old. The serum of this animal 

 gave a border line reaction, which it was impossible to interpret, 

 either as negative or positive.. This reaction might be explained 

 by the fact that this animal, although not affected with con- 

 tagious pleuro-pneumonia, was the progeny of an infected mother, 

 who showed active lesions of the disease on post-mortem exam- 

 ination. No. 86 was an apparently healthy bull, and no lesions 

 of contagious pleuro-pneumonia could be demonstrated in the 

 lungs on post-mortem. This bull gave a border line reaction to 

 the test, which could not be interpreted, either as negative or 

 positive. 



It will thus be seen that, with the exception of the three re- 

 actions specially quoted, the complement fixation test has proved 

 reliable in differentiating between animals which are, and which 

 are not, affected, with. contagious pleuro-pneumonia. 



During the progress of these latter complement fixation tests 

 with alcoholic extracts as antigen, my attention was directed 

 to an abstract, published in the Tropical Veterinary Bulletin, Vol. 

 & (March 30th, 1920), p. 55, of an article, " Feststellung Der 



