Fig. 7-8. Multiple amino acid alignment of the shikimate 

 dehydrogenase domain of AroD»E and its homologues. Nine pro- 

 teins have been aligned and conserved regions are boxed. The 

 probable domain for the NADPH binding site is underlined. The 

 amino acid residue numbers for each sequence are on the right 

 of the figure: 



Designation 



Organism 



Protein 



Accession 

 Number 



Eni-QutB EmericeIJa nidulans 



Ncr-Qa-3 Neurospora crassa 



Ncr-Qa-lS Neurospora crassa 



Eni-QutR Ewericella nidulans 



Sce-Arol Saccharomyces cerivisiae 



Eni-AroM Emericella nidulans 



Eco-AroE Escherichia coJi 



Nta-AroD«E Nicotiana tabacum 



Eco-URF Escherichia coli 



quinate dehydrogenase P25415 



quinate dehydrogenase P11635 



quinate repressor protein P11637 



quinate repressor protein M59935 



arom pentafunctional protein P08566 



arom pentafunctional protein P07547 



dehydroquinase P15770 

 bifunctional S-protein 



unidentified reading frame P28244 



