84 The Philippine Journal of Science 1918 



though a few were brought in from Flanders. Woodcock (25) 

 had previously reported similar cases that had been received 

 from Gallipoli, which he thought were infections with Isospora. 

 The cysts he saw contained one and sometimes two masses of 

 protoplasm. Dr. G. C. Low also came across one case, and 

 Wenyon saw three others at the London Hospital. 



Wenyon(2l) has reported briefly but intelligibly on these 

 three cases and confirms Woodcock's conjecture that his cases 

 were of Isospora infection. Wenyon comments on these cases 

 as follows : 



As the coccidium develops in the intestinal epithelium, it of course brings 

 about destruction of the epithelial cells themselves, and so must be regarded 

 as of some pathogenic importance, although the symptoms of human intes- 

 tinal coccidiosis have not been definitely determined. In animals, such in- 

 fections are often the cause of serious enteritis, which may have a fatal 

 termination. 



Wenyon continued his study of this parasite (22) and figures 

 the oocysts in various stages of development. The cysts are 

 oval, measuring 27 ti to 30 (x by 12 /x to 15 /x, and contain two spo- 

 rocysts, each containing four sporozoites and a mass of residual 

 protoplasm. 



In still another paper (20) this same author reports a case of 

 infection with Coccidium in a soldier invalided home from Gal- 

 lipoli. This case is interesting in that the cysts passed by this 

 patient did not in the least resemble the cyst of the rabbit 

 Coccidium, but more closely resembled the cysts of Coccidium 

 falciforme found in the intestine of the mouse. They were al- 

 most spherical, measuring 20 /x in diameter, whereas Coccidium 

 cuniculi of the rabbit produces oval cysts that measure 28 ^ 

 to 42 ix by 14 fx to 28 fx. The oocyst of this coccidium, as is to be 

 expected, contains four sporocysts, each containing two sporo- 

 zoites and a mass of residual protoplasm. In addition to this, 

 the oocyst of Wenyon 's Coccidium was not smooth externally 

 like that of Coccidium cuniculi, but was covered with irregular- 

 ities in the form of small nodular ridges and elevations, and the 

 same condition was seen in the sporocysts. Wenyon states that 

 while his Coccidium resembles most nearly that of the mouse, 

 it is impossible for him to state definitely if it is actually this 

 species or one quite distinct. 



Briefly discussing the matter of the infection of man with 

 both Isospora and Coccidium, Wenyon says the question is one 

 of great interest. Infection, he says, undoubtedly takes place 

 by way of the mouth, but whether the dust, food, or water, or 

 all three of these are involved remains to be determined. He 



