100 The Philippine Journal of Science wis 



January 29 this animal received intraperitoneally 8 grams 

 of quinine sulphate dissolved in 1,000 cubic centimeters of sterile 

 distilled water slightly acidulated with sulphuric acid. The 

 injection was made at this time to try to abort the disease. In 

 two hours after this injection the carabao was lying down, eating 

 little, and presenting slight nervous symptoms. 



January 30, this animal was standing up and eating well, but 

 had a forenoon temperature of 38.9° C. and an afternoon tem- 

 perature of 39.5° C. 



January 31, afternoon temperature 40.5° C. The animal 

 looked bright and was eating well. 



February 1, forenoon temperature 39.9° C. ; administered intra- 

 peritoneally 10 grams of quinine sulphate dissolved in 1,000 cubic 

 centimeters of acidulated 0.85 per cent sodium chloride solution ; 

 afternoon temperature 40° C. ; not eating; carabao standing up. 



February 2, forenoon temperature 39° C; diarrhoea starting; 

 slight discharge from eyes ; administered subcutaneously 8 cubic 

 centimeters of fluid extract of ergot; afternoon temperature 

 39.8° C. ; diarrhoea, not eating. 



February 3, forenoon temperature 39.7° C; animal very sick; 

 sunken eyes ; arched back ; drooling ; grinding teeth ; swallowing 

 frequently; diarrhoea, not eating; blood-stained slugs of mucus 

 in faeces; administered 10 cubic centimeters of fluid extract 

 of ergot subcutaneously. 



February 4, carabao 67 found dead in the morning; autopsy 

 presented good lesions of rinderpest. 



EXPERIMENT 0. QUININE SULPHATE AND IODINE 



Batanes coiv U168. — This animal was injected January 19, 

 1917, with 50 cubic centimeters of virulent rinderpest blood 

 from bull 4164. 



January 22, this animal presented its first rise in temperature, 

 registering, in the forenoon, 39.7° C; administered intraperi- 

 toneally 2 grams of quinine sulphate dissolved in 500 cubic cen- 

 timeters of acidulated sodium chloride solution and intravenously 

 with 1,000 cubic centimeters of sodium chloride solution in which 

 0.75 gram of iodine and 2 grams of potassium iodide had been 

 dissolved; afternoon temperature 39.7° C. ; muzzle moist; urine 

 dark. 



January 23, forenoon temperature 40° C; animal looked 

 bright; eating; faeces slightly coated with mucus containing a 

 few flakes of blood; administered intraperitoneally 3 grams of 

 quinine sulphate dissolved in 500 cubic centimeters of acidulated 

 0.85 per cent sodium chloride solution; afternoon temperature 



