xiii, b, 2 Boynton: Treatment of Rinderpest 101 



40.5° C. ; animal active; muzzle moist; nostrils looked normal; 

 eating little. 



January 24, forenoon temperature 39.5° C. ; no diarrhoea; 

 looked bright; eating little; administered intraperitoneally 3 

 grams of quinine sulphate dissolved in 500 cubic centimeters of 

 acidulated sodium chloride solution. 



Afternoon temperature 40° C. ; not eating. 



January 25, forenoon temperature 39° C; slight diarrhoea; 

 not eating; swallowing frequently; grinding teeth; looked fairly 

 bright; administered intraperitoneally 3 grams of quinine sul- 

 phate dissolved in 500 cubic centimeters of acidulated sodium 

 chloride solution. 



Afternoon temperature 39.6° C. ; diarrhoea, not eating. 



January 26, cow 4168 found dead in the morning; autopsy 

 presented marked lesions of rinderpest; intestinal hemorrhage 

 very pronounced. 



EXPERIMENT 10. QUININE SULPHATE, IODINE, AND ERGOT 



Batanes cow U172. — This animal was injected January 22, 

 1917, with 50 cubic centimeters of virulent rinderpest blood 

 from No. 4186. 



January 25, this animal presented its first rise in temperature, 

 registering in the afternoon 40.3° C. 



January 26, forenoon temperature 39.3° C. ; diarrhoea, not 

 eating; administered intraperitoneally 5 grams of quinine sul- 

 phate dissolved in 500 cubic centimeters of acidulated sodium 

 chloride solution. It was also injected intravenously with 1,000 

 cubic centimeters of sodium chloride in which had been dissolved 

 1.5 grams of iodine and 4 grams of potassium iodide. The ani- 

 mal withstood the injection well. The afternoon temperature 

 was 38.4° C, which was the average normal temperature for 

 the healthy animals this day. 



January 27, forenoon temperature 38.2° C. ; diarrhoea, not eat- 

 ing; animal did not possess good coordination of movement; 

 muzzle moist; administered subcutaneously 8 cubic centimeters 

 of fluid extract of ergot; afternoon temperature 38.8° C. 



January 28, forenoon temperature 37.7° C. ; diarrhoea, not eat- 

 ing; animal lying down; respiration catchy; blood in faeces; 

 large amount of mucus; administered subcutaneously 5 cubic 

 centimeters of fluid extract of ergot. 



Afternoon temperature 38.8° C. ; diarrhoea ; better in appear- 

 ance ; breathing regular ; lying down ; not eating, but drinking 

 a little. 



January 29, animal found dead in the morning. Upon autopsy 



