XIII, 



B > 3 Boynton: Virulence of Body Organs in Rinderpest 143 



June 29, 1917, bull 4302 received subcutaneously 100 cubic 

 centimeters of a 20-day-old 1 per cent phenol extract of lymph 

 glands from bull 1034 (P. C. W.) (see experiment 19). 



July 2, this animal presented its first rise in temperature, 

 registering, in the afternoon, 40.2° C. 



July 3, forenoon temperature, 39.6° C. ; afternoon, 40.2° C. 



July 6-7 diarrhoea, not eating; died during the afternoon of 

 July 7. This animal presented typical symptoms and lesions of 

 rinderpest. 



EXPERIMENT 21 



Phenol (1 per cent) extract of liver, 21 days old. 



Bull 4303. — Known history prior to experiment : Native Fuga 

 bull, 3 years old, received at the laboratory and placed in quar- 

 antine June, 1, 1917. This animal was kept under observation 

 twenty-nine days before it was used; it did not present a high 

 temperature or develop any symptoms of sickness during this 

 period. 



June 30, 1917, bull 4303 received subcutaneously 100 cubic 

 centimeters of a 21-day-old 1 per cent phenol extract of liver 

 from bull 1034 (P. C. W.) (see experiment 19). 



This animal ran a rather erratic temperature from July 3 

 until death. 



July 9, diarrhoea; afternoon temperature, 40° C, which was 

 the highest temperature registered during the course of the 

 disease. 



July 10, diarrhoea. 



July 11, diarrhoea, not eating; afternoon temperature so low 

 that it could not be read. 



July 12, found dead in the morning. This animal developed 

 rather atypical symptoms, which do sometimes occur in rinder- 

 pest. (3) It presented good lesions of the disease. 



EXPERIMENT 22 



Phenol (1 per cent) extract of spleen, 21 days old. 



Bull U30U. — Known history prior to experiment : Native Fuga 

 bull, 2 years old, received at the laboratory and placed in quar- 

 antine June 1, 1917. This animal was kept under observation 

 for twenty-nine days before it was used; it did not present a 

 high temperature or develop any symptoms of sickness during 

 this period. 



June 30, 1917, bull 4304 received subcutaneously 100 cubic 

 centimeters of a 21-day-old 1 per cent phenol extract of spleen 

 from bull 1034 (P. C. W.) (see experiment 19). 



154722 2 



