214 The Philippine Journal of Science 1913 



■ 



by its author, Doctor Samson. It was discussed by Professor 

 Haughwout. 



The society adjourned at 9.55 in the evening. 



D. de la Paz, 

 Secretary-Treasurer. 



iADiaaw. 



SCIENTIFIC PROGRAM 



STUDIES OF THE CEREBROSPINAL FLUID IN ACUTE ANTERIOR 



POLIOMYELITIS 1 



By John A. Kolmer and co-workers 

 Abstracted by Dr. John A. Johnston 



The results summarized in this paper are based upon the ex- 

 aminations made in 868 specimens of cerebrospinal fluid obtained 

 during the epidemic in Philadelphia during 1916. 



A summary follows:, 



1. The majority of the fluids were water clear or but faintly 

 opalescent when viewed against a black backgroundi 



2. Seventy-seven per cent of the fluids showed an increase of 

 total cells. .,,. ,..■••,., 



. 3. In over 96 per cent of the fluids from cases after the onset 

 of paralysis the small lymphocyte variety of cells predominated. 

 Polymorphonuclear cells predominated in less than 1 per cent of 

 the fluids, and in over 88 per cent they constituted less than 25 

 per cent of the cells present. 



4. An increase of protein was found in from 32 to 42 per cent 

 of fluids. With the Noguchi test the fluid of 1 of 6 cases in the 

 preparalytic stage yielded a positive reaction. The percentage 

 of positives then became gradually higher to the third week after 

 the onset of paralysis, when a rapid decrease in protein became 

 apparent. 



5. During the acute stages of poliomyelitis the fluids of 40 

 to 50 per cent of cases yielded a colloidal gold reaction of the 

 luetic and meningitic zone types. 



6. The potassium permanganate reduction test yielded positive 

 reactions of indices over 2.3 with the spinal fluids of 41 per cent 

 of cases examined from the second to twenty-first days after the 

 onset of paralysis. 



Every fluid was found to contain sufficient dextrose to reduce 

 Fehling's solution in some degree. 



8. Increased permeability of the meninges was indicated by 

 the presence of natural antisheep hemolysis in the fluids of 66 

 per cent of cases in the acute stages and both the hemolysis and 



1 Am. Journ. Med. Sci. (1917), 144, 720-733. 



