THE PHILIPPINE 



Journal of Science 



Vol. XIII 



B. Tropical Medicine 



SEPTEMBER, 1918 



No. 5 



THE TISSUE-INVASIVE POWERS OF THE FLAGELLATED AND 

 CILIATED PROTOZOA WITH ESPECIAL REFERENCE TO 

 TRICHOMONAS INTESTINALIS. A CRITICAL REVIEW* 



By Frank G. Haughwout 1 



(From the Department of Medical Zoology, College of Medicine and Surgery, 



University of the Philippines) 



ONE TEXT FIGURE 



The recent work of Hadley, (20) in which he has demonstrated 

 that under certain conditions, so far unascertained, Trichomonas 

 may become a destructive cytozoic and histozoic parasite, has 

 again brought up the question of the tissue-invasive powers and 

 pathogenicity of the flagellated and ciliated protozoan parasites 

 found in the intestine of man. The question is of such prime 

 importance in the practice of medicine, particularly in the 

 tropics, that it seems opportune at this time to review some 

 of the literature on these very important subjects. It must be 

 confessed at the beginning that it seems impossible to draw 

 any very definite conclusions; but force is added to the already 

 very prevalent impression that the flagellated intestinal proto- 

 zoa should be viewed with suspicion and regarded as pathogenic 

 until the contrary is proved beyond dispute. 



From the viewpoint of human pathology the matter can be 

 scarcely discussed at this time, for with the exception of Balanti- 

 dium infections of the human intestinal tract there are no obser- 

 vations upon which to work. The whole problem from the 

 clinical, pathological, and experimental viewpoints presents ex- 



* Received for publication March 15, 1918. 



1 Professor of protozoology and chief, department of medical zoology. 



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