xiii, b, 5 Haughwout: Flagellated and Ciliated Protozoa 237 



This again gives rise to the question as to whether Trichomonas 

 as it appears in the intestinal tissues of man, if it does, so closely 

 resembles Entamoeba as to have been mistaken for the latter 

 by the skilled observers who for years have been studying sec- 

 tions of the human intestine taken from cases of dysentery. 

 Hadley's sections of the turkey caecum ought to throw consider- 

 able light on this matter. 



Castellani described his organism in 1905 as Lbschia undulans. 

 Gauducheau has reported a similar organism in the fasces of 

 dogs. Wenyon(50) has already called attention to the similarity 

 that Trichomonas bears to Entamoeba undulans when the former 

 is casting off its motile apparatus and assumes the amoeboid 

 form. The case reported by Castellani was in a European 

 planter of Ceylon, who gave a history of entamoebiasis of the 

 intestine and liver. His stool contained, in addition to the or- 

 ganism described by Castellani, Entamoeba and Trichomonas. 

 The organism measured 12 to 30 [i, but smaller forms were 

 occasionally encountered. They had no flagella. There was a 

 distinct undulating membrane along one border. Long, straight, 

 finger-formed pseudopodia were rapidly extended and retracted, 

 one at a time. No ecto- or endoplasmic differentiation was 

 noted. The cytoplasm was finely granular and contained bac- 

 teria and a noncontractile vacuole. 



There now seems little doubt that Castellani's Entamoeba undu- 

 lans is Trichomonas. The appearances described by him coin- 

 cide so closely with developmental changes that have been seen 

 in Trichomonas as practically to banish doubt on this point. 



In the general consideration of these matters it seems worth 

 while in passing to mention briefly Ijima's Amoeba miurai, de- 

 scribed by him (23) and by Miura.(37) It is not by any means 

 certain that the bodies described by these two Japanese workers 

 were living organisms. Many writers voice the opinion that 

 they were tissue cells present in a serous exudate. In any 

 event, the bodies were spherical or ellipsoidal. One end bore 

 a small protruberance from which sprang several filamentous 

 processes described as pseudopodia, but which more closely re- 

 sembled cilia. The whole body measured from 15 to 38 /x. The 

 cytoplasm was granular with no ecto- or endoplasmic differentia- 

 tion. It contained several vacuoles, none of which was contrac- 

 tile. One to three nuclei were demonstrated on the addition of 

 acetic acid. The bodies were discovered in the serous fluid of 

 a young woman, who had died of pleuritis and peritonitis endo- 

 theliomatosa. Similar forms appeared two days before death in 

 the bloody stool of the patient. Amoeboid motion was not noted. 



