$4i4t CALCVLJ. 



Kxperiments IB ay be Confirmed, in thfr pjmthetic way; having resolvedj 

 Sts^^on'^ine *^** experiment, as far as applicable, should form the ba, 

 ^. 'sis of any opinions, offered in this essay. The phosphoric 



being the native acid, prevalent in urine, it was interest, 

 ing to determine, whether, by the artificial super-addition 

 of it, so as to bring this fluid to the standard of the gouty, 

 we might not produce effects, somewhat analogous to wl^at 

 occur there. 



Eighteen ounces of urine were divided into three equal 

 parts. To the first were added, five drops of phosphoric 

 acid; to the second, ten; and to the third, fifteen. In the 

 first, the magnifier very soon discovered minute floating 

 moleculae, gradually assuming the crystalline form, &c. as 

 ^o often before described. In the secqnd, the same ap- 

 pearances, but more immediately and copiously proi^uv'ed. 

 But in the third, so considerable, as to excite my asto- 

 nishment. For here, besides the same extremely minute 

 - crystals, which adhered to the entire sides of the phial, 

 the bottom appeared covered with a mixture of crystal, 

 line, and red pulverulent matter : the latter in a great pro- 

 portion, and, probably, prevented from crystallization, by 

 its hasty deposition. Here, then, that encreased propor- 

 tion of calcareous phosphat and animal gelatinous mat- 

 ters, (which always takes place in gout, and could not be 

 expected here,) would seem only wanting, to form a sort 

 of synthetic approximation to the gouty sediment. 



The unusual proportion of deposited uric acid, in this 

 experiment, created some suspicion, that the phosphoric 

 acid might, by a combination with some of the principles 

 of this very compound fluid, give rise to some artificial for- 

 mation of it on this occasion. 



To the filtered liquor, therefore, of Number 3, were 

 again superadded five drops, which, in twenty-four hours, 

 caused a farther separation of a very few crystals only. — 

 It Avas filtered a third time, and eight drops more added ; 

 but without the smallest appearance of a single crystal, 

 after four days. The additional acid, then, only more eff"ectu. 

 ally and speedily determined the separation of the quantity, 

 naturally contained in urine: its more divided pulverulent 

 appearance adding considerably to its volume. 



It 



