502 ACTION OF VEGETABLE POISONS, 



numbness of the lips and gums, which does not subside for 

 two or three hours. 



Experiments with the Infusion of Tobacco. 

 Effects of 10- Exp. 8. Four ounces of infusion of tobacco were injected 

 FspftimentS. *"*o *^^ rectum of a dog. Four minutes afterward he 

 retched, but did not vomit J he then became faint, and lay 

 motionless on one side ; at the end of nine minutes from the- 

 time of the injection, the heart could not be felt ; he gasped 

 for breath at long intervals : and in another minute there 

 was no appearance whatever of life. I immediately laid 

 open the cavities of the thorax and abdomen. The heart 

 was much distended, and had entirely ceased to contract; 

 there was no peristaltic motion of the intestines, 

 flxperiment 9. Exp. 9. An ounce of very strong infusion of tobacco was 

 injected into the rectum of a cat. Symptoms were pro- 

 duced similar to those, which occurred in the last experi- 

 ment, and the animal died at the end of seven minutes from 

 the time of the injection. On opening the thorax immedi- 

 ately after death, the heart was found extremely distended, 

 and to have entirely ceased acting, with the exception of a 

 slight tremulous motion of the auricles. 

 Exp. 10. Exp.lO. Three ounces of infusion of tobacco were in- 



jected into the rectum of a dog. He was affected with 

 symptoms similar to those in the former experimeutsv, and 

 died at the end of ten minutes. On opening the thorax im- 

 mediately after death, I found the heart much distended, 

 and to have entirely ceased contracting. 

 Exp. II. Exp. \\» Three ounces of infusion of tobacco were in- 



jected into the rectum of a dog. Immediately there tock 

 place tremulous contractions of the voluntary muscles. 

 Five rainates afterward the injection was repeated in the 

 same quantity. The dog then was sick, and threw up some 

 of the infusion, with other matter, from the stomach; he 

 became faint, and died ten minutes after the second injec- 

 tion. Immediately after respiration had ceased, I opened 

 the thorax, and found the heart extremely distended, and 

 ■without any evident contraction, except of the appendix of 

 the right auricle, which every now and then contracted in'-a 

 slight decree. I divided the pericardium on the right side. 



In 



