35G 



ANALYSIS OF DEADLY NIGHTSHADE. 



The woody 

 part. 



Its properties 

 owing to the 

 part soluble in 

 alcohol, , 



This proved on 

 a dog. 



Experiment 1. 



Effects. 



Experiment : 



Experiment 0. 



Effects. 



3, Several salts with base of potash, namely, a great 

 deal of nitrate, some muriate, some sulphate, acidulous 

 oxalate, and acetate. 



The substance of the belladonna, from which the juice 

 had been expressed, having been washed with hot water, 

 dried, aod then burned, left ashes composed of a pretty 

 large qsantity of lime, phosphate of lime, iron, and silex. 



This lime announces, that the plant contained oxalate of 

 lime, which had been decomposed by the fire. 



There can be no doubt, that it is the matter in' bella- 

 donna soluble in alcohol, which alone produces its delete- 

 rious effect on the animal economy; for it is the only sapid 

 part, and the well known effects of all the other mat- 

 ters accompanying it in no reject resemble those of the 

 plant. 



To place this beyond doubt, I gave a middle-sized dog 

 a certain quantity of this principle mixed with his food. 



A quarter after twelve I made this dog take 1 gr. 

 [15.45 grs.] of the extract rolled up in 10 gr. [154*5 grs.] 

 of bread and meat made into a paste. 



In three quarters of an hour the animal appeared in- 

 clined to sleep ; he held his head down, and seemed unable to 

 support it ; he lay down several times with his head on the 

 ground ; his paws were slightly convulsed ; his jaws moved 

 for some time, as if he were chewing, These effects con- 

 tinued about three quarters of an hour, but nothing farther 

 ensued, and the dog resumed his ordinary manners. 



At 2 o'clock in the afternoon I gave hiin 2 gr. [30*89 grs.] 

 of the extract in 12 gr. of paste. The effects were re- 

 newed ; but they were slighter, and of shorter duration. 



At 3 o'clock 'I made him swallow 4 gr. [61-78 grs.] of 

 the same extract, with about 30 gr. [363 grs.] of paste. 



A few minutes after he was seized with a continual but 

 uncertain and difficult movement; chiefly in the abdominal 

 extremities ; and uttered some plaintive cries. 



At half after three he found great difficulty in moving 

 himself; he dropped frequently on his hind feet; and his 

 respiration was very much confined. He attempted several 

 times to go through the wall, which showed assort of de- 

 lirium. He had then a trembling in all his muscles. 



At 



