XII, B, 1 



Garcia: Common Intestinal Parasites 



31 



resulted, as shown by the negative microscopic findings of the 

 stool. 



To observe the effects of broken doses, the same drugs with 

 the same amounts were given as follows: 



Nothing to eat; stop all other medicine and give magnesium sulphate 

 saturated solution, 40 cubic centimeters. 



After two hours give thymol, grains XL, in four doses at half-hour 

 intervals. 



After the last dose, repeat magnesium sulphate saturated solution. 



For Ascaris treatment the following was substituted : 



Give the following formula in four broken doses, half hour apart: 



Santonin grains V 



Calomel grains II 



Sodium bicarbonate grains V 



After three hours of last dose, give magnesium sulphate saturated solu- 

 tion, 40 cubic centimeters. 



These broken doses were given for two months, and the effects 

 were compared with those in which the drugs were given in one 

 dose for two months also. 



Table VI. — Comparison of effects of one dose and of broken doses. 



ASCARIS. 



Results of one dose. 



Results of broken doses. 





Treatments 





Treatments 



Persons 

 treated. 



given to 



produce 



negative 



finding for 



Persons 

 treated. 



given to 



produce 



negative 



finding for 





ova. 





ova. 



4 



2 



6 



2 



2 



3 



2 



3 



1 



6 



1 



4 



1 



7 



1 



7 



HOOKWORMS. 



3 



1 



11 



1 



3 



2 



1 



2 



2 



4 









1 



From the tabulation it will be seen that the results of the treat- 

 ment of Ascaris did not vary greatly, whether the formula was 

 given in one dose or in four broken doses. As to hookworm 

 treatment, it seems from the observation of the 8 and 12 cases 

 that the broken doses are more effective in eliminating the 

 hookworms than when giving the thymol in one dose. 



