XII, B, 2 Mendoza-Guazon: Anatomicopathologic Lesions 81 



and only one from 2 to 5 years in his clinical report of 27 

 hospital cases. 



Typhoid in children has a mild course, and Percy, (40) in his 

 clinical report of 380 cases, did not see any perforation. 



Foetal typhoid has not been reported in Manila as far as we 

 know. The study of Morse (36) is nevertheless worthy of note. 

 He comes to the following conclusions: 



Infection of the child from the mother is a frequent, but not an in- 

 variable occurrence. The bacilli may pass directly from the maternal into 

 the foetal circulation. The foetal form of disease is a general blood in- 

 fection since the intestines are not functionally active. The most common 

 result is death of the foetus and consequent abortion ; but the child may 

 be born alive still suffering from infection and die in a short time because 

 of its feeble resistance. Whether a foetus may recover completely and be 

 born alive and well is not yet established. 



Griffith and Ostheimer,(23) in 302 cases of typhoid in children 

 under 2^ years of age, found 2 cases of perforation. 



MALARIA 



In spite of the fact that malaria is prevalent in the tropics 

 and is met with in pregnant women of the Philippine General 

 Hospital, (49) we have no record of an intrauterine infection. 



The pathological lesions were similar to those found in adults. 

 In this series 6 cases are found; the youngest is a girl 1^ years 

 old. 



TUMORS 



Six cases of tumors are found in this series : 2 cases of glioma 

 of the eye, 1 of fibromata of the capsule of the liver (autopsy 

 2057), 1 of adenoma of the intestine, and 1 of neuroblas- 

 toma of the adrenal, which was diagnosed macroscopically as 

 tuberculosis. Autopsy 1538 shows enlargement of the pineal 

 gland, measuring 15 by 10 by 3 millimeters, which presses 

 upon the aqueduct of Silvius. In the wall of the intestine 

 is noticed a small grayish red area 1 by 0.5 by 0.5 centimeter, 

 which is firm, and section shows a glistening grayish red sur- 

 face and definite cellular structure. Beneath the endocardium 

 of the heart, more especially on the left than the right ventricle 

 and also in the muscular wall of the left ventricle, are noticed 

 a few small, firm grayish white areas. 



Histological examination shows adenoma of the intestine and 

 oedematous myoma of the heart. (B. C. Crowell.) 



SUMMARY 



This study on the anatomicopathologic lesions of Filipino 

 children under 5 years shows that : 



(1) Hemorrhage is the most frequent cause of death during 



