82 ^^6 Philippine Journal of Science 1917 



the first few days of life and that the brain and meninges are the 

 favorite seats. Congenital anomalies are also responsible in 

 many instances. 



(2) Of the children in this series 15.9 per cent are infected 

 with nematodes, and the frequency of infestation increases as 

 age advances. The first variety that invades the alimentary 

 tract of children and the one that infects the most is Ascaris 

 lumbricoides, 95.5 per cent. This worm shows also a great 

 migratory activity, which is probably favored by an abnormal 

 condition of the intestines. 



(3) The most frequent concomitant lesion of gastrointestinal 

 disease is bronchopneumonia. In 193 cases the morbid condi- 

 tion was located in the colon in 68 and in both intestines 

 in 54 cases. Amoebic dysentery is very rare in children, there 

 being only one recorded case, and yet the lesions as described 

 are not typical. 



(4) Asiatic cholera was nil during April and May, the inci- 

 dence increasing with age and during epidemics. Newly bom 

 infants can be infected during their existence from a mother 

 suffering with the disease. 



(5) In infants it is almost the rule for tuberculosis to become 

 generalized rather than localized, the lungs being the commonest 

 seat of lesion and the aerogenic type the most frequent mode of 

 infection. The pericardium, oesophagus, duodenum, rectum, gall 

 bladder, and reproductive system were not affected in this series 

 even in a generalized acute and diffuse infection. Tuberculosis 

 in this series has been found in 80 cases. 



(6) Infantile beriberi has been anatomically diagnosed in 150 

 cases. The literature shows that the disease is met only in 

 infants born of, or nursed by, women on an exclusive rice diet. 

 It is not seen in Manila in the children of foreigners that do 

 not eat much rice. If the neuritis-preventing substance is de- 

 stroyed by heat, can we produce infantile beriberi by feeding 

 healthy infants with heated milk of nursing women whose diet 

 is other than polished rice or can it only be produced by the milk 

 of healthy women who live exclusively on polished rice ? 



(a) If the anatomic findings of infantile scurvy are similar 

 to those of infantile beriberi and good results can be expected 

 by the use of middlings in the first and tiqui-tiqui in the latter, 

 would we get the same good results if we change the treatment? 



(b) The experiments on scurvy by Ingier and by Goldmann 

 and the findings of Gibson and Concepcion(2i) seem to be contra- 

 dicted by the explanation given by some Japanese and local 

 students of infantile beriberi that the beriberi-preventing prin- 



