102 The Philippine Journal of Science 1917 



SYNOPSIS 



The intestinal contents and the bile of 269 cases of cholera and 

 cholera carriers have been examined. In 212 cases of cholera 

 the vibrio was found in the bile in 65.2 per cent and only in 

 the bile in 5.7 per cent. In 32 cholera carriers detected after 

 death, the cholera vibrio was found in the bile in 75 per cent 

 and only in the bile in 43.7 per cent. 



In examining a large series of cholera cases the vibrio may 

 not be recovered from the faeces in a certain number in whicH 

 it is recovered from the bile. In cholera carriers the vibrio 

 was present in this series in the bile in 10 per cent more cases 

 than in cholera cases and only in the bile in 38 per cent more 

 than in cholera cases. From this the importance of routine 

 examination of both bile and faeces becomes apparent. 



Five cases that were known to have been carriers before 

 death were examined after death, and only in the one with the 

 shortest period between detection and death (thirty-seven days) 

 was the vibrio found. In that case the vibrio was isolated from 

 the bile only. 



Thirty strains of nonagglutinable vibrios, isolated from the 

 faeces and bile of cholera cases, cholera contacts, and others, 

 have been studied. When first isolated, these were not aggluti- 

 nated by high-titer cholera-immune serum. By growth in bile 

 8 of these strains acquired the agglutinability. Five of these 

 8 strains .retained this property, and the other 3 lost it after 

 cultivation for a period of two months. 



In 6 cases that were clinically and anatomically cholera, the 

 cholera vibrio was not isolated from either the faeces or the bile. 

 Such cases occur in a large series of cholera cases. 



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10. Idem. Ibid. (1913), 1, 59. 



11. Idem. Ibid. (1913), 1, 65. 



12. Idem. Ibid. (1913), 1, 90. 



13. Idem. Ibid. (1913), 1, 290. 



14. Idem. Ibid. (1914), 2, 1. 



15. Idem. Ibid. (1914), 2, 28. 



