150 The Philippine Journal of Science im' 



In those monkeys in which infection took place, the balantidia entered 

 the tissues through the sound intestinal epithelium. 



Balantidium coli can produce bacteriologically sterile abscesses in the 

 submucosa of an infected intestine. 



Balantidium coli is the primary etiologic factor in the symptoms and 

 lesions of balantidial dysentery. 



The latency prevalent in balantidiasis of man is due chiefly to the fact 

 that the patient, although parasitized, is not infected with Balantidium 

 coli, but in part to the chronicity of the ulcerative process in infected cases. 



Walker, in examination of the intestines in the early stages 

 of the infection, found the epithelium intact except for a me- 

 chanical injury, which he attributed to entrance of the balantidia 

 or to minute hemorrhages, but there was no exudate or ulcera- 

 tion. He found more or less congestion of the blood vessels, 

 and the tissue infiltration, which was slight, was of round cells 

 and eosinophiles. Those sections of the colon which did not 

 show balantidia showed either a catarrhal or diphtheritic exu- 

 date or ulceration, usually associated with polymorphonuclear 

 infiltration of the mucosa and submucosa. 



The histological report of Strong is similar to that of Solow- 

 jew, which is as follows: 



The parasites were found invading the mucosa, submucosa and muscular 

 layers. They were less numerous in the areas which showed marked necrosis 

 and were found in the margins of more healthy tissue which surrounded 

 these areas. The capillaries of the mucosa and submucosa were dilated, 

 contained parasites and often showed hemorrhage about them. Often the 

 amount of infiltration was small about single parasites in the tissues. 

 However, when the parasites were found in large numbers the infiltration 

 was very marked. The ulcerations extended in places down to the muscular 

 coat, and their edges were usually undermined. The lymph glands were 

 hypertrophied and hyperemic. No parasites were found in any other organ 

 than the large intestine. In the mesenteric glands, spleen, liver, and 

 kidneys there was considerable pigment inside the leukocytes in the blood 

 vessels. No tubercle bacilli were found in the sections. 



CASE REPORTS 



CASE I 



History. — The first case to be reported is one of a Filipino 

 male, age 16, who was admitted to the Philippine General Hos- 

 pital on March 1, 1916, at 3.30 in the afternoon, complaining 

 of bloody diarrhoea, weakness, and loss of weight. Nothing 

 could be determined as to his method of living or concerning 

 the family and past history beyond the fact that he attended 

 school. 



The first intestinal symptoms began about two months pre- 

 vious to admission to hospital with frequent bloody bowel move- 



