ECKINOSTOMA ILOCANUM (GARRISON): A REPORT OF FIVE 

 CASES AND A CONTRIBUTION TO THE ANATOMY OF THE 



FLUKE 1 



By J. S. HiLARio'' and L. D Wharton" 

 (From the Departments of Pathology and Medical Zoology, University 



of the Philippines) 



ONE PLATE AND ONE TEXT FIGURE 



In October, 1916, an ovum was found in the clinical laboratory 

 of the Philippine General Hospital, Manila, measuring 90 microns 

 in length and 50 microns in width and bearing the same morpho- 

 logical characteristics as described by Garrison in 1907. 



It is oval in shape with one end more sharply rounded; the shell is 

 light brown in color, smooth and rather delicate, with an operculum at the 

 sharper end; the contents are rather refractile, colorless, and composed of 

 a mass of yolk-cells, among which the germ cell could in some cases be 

 recognized. 



Large numbers of ova of this description were collected from 

 the first two cases, and they were placed in distilled water and 

 in saline solution and were preserved in alcohol after fixation in 

 acetic sublimate. 



After a careful study of the material on hand a tentative 

 diagnosis of Echinostoma ilocanum was made, which was later 

 confirmed by Professor Crowell and one of us (Wharton) in a 

 fresh specimen. 



Through the courtesy of Dr. E. Domingo, from the department 

 of medicine, it was possible for us to secure the worms after a 

 dose of male fern. Eight worms were obtained from the first 

 case, the specimen of stool from the second case failing to show 

 any. The treatment consisted of 24 capsules of oleoresin of 

 male fern given in doses of 4 capsules every ten minutes. During 

 the previous day the patient was kept on liquid diet without milk 

 as a preparatory measure for the next day's treatment. 



The detection of the worm in the stool is fraught with no little 

 difficulty on account of its small size, its flat body, and its appear- 

 ance, which makes it hardly distinguishable from the small parti- 



' Received for publication April, 1917. 



* Assistant professor of pathology. 



^ Assistant professor of zoology. 203 



