xii,B,6 Manlove: Incidence of Age 247 



much as 2 centimeters deep in places and begins just above the aortic valve. 

 The walls of the entire portion are inelastic, and the intima is roughened 

 with plaques which are flat, soft, elevated, and whitish to yellowish. These 

 plaques measure from 0.5 to 1 centimeter in diameter and about 2 milli- 

 meters in height. Throughout the remaining portion of the thoracic and 

 abdominal aorta the intima sh3ws the presence of some whitish to yellowish 

 elevated plaques of 0.5 to 1 centimeter in diameter. The iliac arteries are 

 apparently normal. 



Spleen. — The spleen is about normal in size and rather soft and is bluish 

 gray. The capsule is smooth. The spleen cuts with some resistance, 

 showing a smooth reddish surface upon which the interstitial tissue is 

 prominent. From thci cut surface exudes some blood-tinged fluid. 



Adrenals. — The adrenals show no appreciable change from normal. 



Kidneys. — The kidneys are about one and a half times the normal in 

 size, but they are about normal in shape. They are surrounded by a small 

 pad of fat, and they are firm. They cut with resistance, showing a smooth 

 surface upon which the pyramids are regular in outline and pale, with a 

 pinkish tint and with some red linear markings at the bases; while the 

 cortex varies in thickness, from thinner to thicker than normal, and the 

 entire cortex is pale, with a pinkish tinge, and appears to be minutely 

 granular. The capsule strips with considerable resistance, showing a 

 surface which is smooth in places and somewhat roughened in others 

 and which is pale. The pelves are apparently normal. 



Intestines. — The intestines are apparently normal. 



Liver. — The liver is brownish. The capsule is smooth. It is about 

 normal in shape and size. It cuts easily; upon the cut surface the lobules 

 are plainly visible, although they appear to be slightly paler than normal, 

 and the outlines are pale. The bile ducts and vessels show no appreciable 

 change. The gall bladder contains some thick, viscid greenish bile, and 

 its mucosa and walls are apparently normal. 



Urinary bladder. — The urinary bladder is contracted and empty. Its 

 mucosa is pale and smooth throughout. 



Brain. — The dura mater strips easily and is pale and smooth. Beneath 

 the pia-arachnoid there is an excess of watery fluid, but the vessels show 

 no appreciable change from normal. 



HISTOLOGY 



Sections were made from the femoral aneurism and from the aneurismal 

 dilatation of the aorta. The sections included a raised plaque upon the 

 intima and were stained with haematoxylin and eosin and were also stained 

 for spirochastes by the Levaditi method. 



Aneurism walls. — There is a thickening of the intima which is composed, 

 of a noncellular hyalinlike substance which has its continuity broken in 

 places. The media in places is infiltrated with round cells, which produce 

 a slight spreading of the muscle fibers. The blood vessels of the tunica 

 externa have thickened walls and narrowed lumens and are surrounded 

 with dense, round-cell infiltration and some endothelial leukocytes. 



Aortic walls. — The aortic walls resemble the aneurism walls with the 

 exception that there is more extensive cellular infiltration of the media 

 with degeneration and a new-forming compact tissue. The vasa vasorum 

 are also more extensively involved than are those of the femoral vessel. 



The sections stained by the Levaditi method do not reveal any structures 

 1B0681 s 



