288 '^^^ Philippine Journal of Science 1917 



imals may have been suffering, thus causing the formation of 

 these bodies in their red blood cells. 



Porter (4) has observed anaplasmalike bodies in the red blood 

 cells of mice, canaries, swallows, martins, lizards, snakes, frogs, 

 toads, and sticklebacks, which are representatives of all the 

 great groups of the vertebrates. These bodies were most prev- 

 alent in animals that were anaerhic. 



Balfour (1) has found anaplasmosis in sick donkeys from 

 Malakas on the White Nile and is led to believe they are true 

 protozoan parasites. 



Spreull(6) has also observed the marginal points in the blood 

 of cattle in South Africa and declares his conviction that the 

 marginal points are parasitic in nature. 



Jowett(3) observed marginal points in the red blood cells of 

 a cat that had been inoculated with a trypanosome infecting 

 cattle in Cape Town, South Africa. This cat was suckling a 

 kitten at the time, and similar bodies were found in the blood of 

 the kitten. He also found similar bodies in the blood of rats 

 infected with this trypanosome and noticed them in the blood 

 of apparently healthy noninfected rats. He also states that — 



In the case of the trypanosome-infected, and consequently anaemic, 

 subjects (both cats and rats) the bodies were, as a rule, more numerously 

 present than in other animals which appeared healthy and which had not 

 formed the subejct of experiment. They were sometimes markedly notice- 

 able in the blood cells of our experimental rats the day following the ad- 

 ministration of a dose of antimony. 



Jowett quotes Bruce, Hammerton, Bateman, and Mackie as 

 having noted the occurrence of marginal points in cattle (espe- 

 cially calves) in Uganda. These investigators refer to these 

 bodies in the following terms: 



If these bodies really constitute a new and undescribed parasite, the 

 discovery will be one of great interest. Bodies similar in every way to 

 these are found, however, in healthy young rats, goats, calves, etc., so that 

 it is difficult to believe at once in their parasitic nature. Rather would 

 they appear to be cell inclosures due to rapid changes taking place in the 

 blood, such as takes place in young animals or in anaemias. 



CONCLUSIONS 



1. Cattle 3929, 3932, and 3939 presented bodies in their red 

 blood cells similar to Anaplasma marginale as described by 

 Theiler and by Sieber. 



2. Cow 3929 presented the symptoms and lesions of anaplas- 

 mosis as described by Theiler and by Sieber. 



3. The heart's blood of cow 3929 was injected subcutaneously 



