XI, B, 3 Gibson and Concepcion: Development of Neuritis 125 



to eat the milk. In as much as starvation contributes to the 

 degenerative change in the peripheral nerves,^^ the dogs were 

 chloroformed on the ninety-second day. 



No scorbutic symptoms were observed in any of the dogs 

 in the course of the experiment. No gross changes were found 

 at autopsy. The endocrin glands appeared normal. Histolog- 

 ical examination of the sciatic nerves revealed degenerative 

 changes for the two dogs fed on fresh cows' milk as well as for 

 the three given autoclaved milk. 



Differences in the rates of growth and the food consumed were 



Days of the experiment. 



» 23 27 



g 



CO 



.a 



CQ 



/.COO 



Fig. 1. Growth curves for dogs fed on fresh and autoclaved milk. 



not great between the dogs fed on fresh and those fed on 

 autoclaved milk ; they were slightly in favor of the former. The 

 growth changes will be discussed later in this paper. 



The dogs soon lost their appetite for the cows' milk, particu- 

 larly for the autoclaved milk. The addition of bone ash (5 grams 

 daily) to the milk of dogs 1 and 6 after the fiftieth day 

 led to better consumption and utilization of the milk. The dogs 

 of each group seemed ravenous when tempted with beef bones, 

 the more so the longer the experiment was continued. 



Our experiment with dogs has shown that exclusive feeding 



** Chamberlain, Bloombergh, and Kilbourne, This Journal, Sec. B (1911), 

 6, 177. 



142020 2 



