XI, B. 4 Schobl: Cholera Culture and Cholera Carriers 156 



previous experiments * to be thirteen days. Animals injected 

 with 1/40,000 and 1/100,000 of a slant were found negative. 

 Again the animal that received the smallest dose, 1/100,000,000, 

 still harbored cholera vibrios on the thirteenth day. 



CONCLUSIONS 



1. Inoculation of a relatively small amount of cholera vibrios 

 into the gall bladder may produce carriers in animals, but the 

 results are not as regular as they are when larger amounts are 

 used for inoculation. 



2. The amount of inoculum seems not to have any direct bear- 

 ing on the duration of the carrier state in animals according to 

 the preceding experiments. The negative animals which were 

 inoculated with 1/40,000 and 1/100,000 are to be interpreted as 

 failure "takes," as the animal that received a far smaller dose 

 was positive. 



•Op. cit. 



