xr. B, 5 Guerrero et al. : lUicium religiosum Siebold 207 



to 40° C. at 10 o'clock in the evening, but later it subsided. 

 The patient urinated seven times during the night. 



On October 8 the general condition of the patient was ex- 

 cellent. There was only slight mental depression, which gra- 

 dually disappeared. The patient recovered completely and had 

 no recollection of anything that had happened after the in- 

 gestion of the poison. He did not remember the approximate 

 quantity of the Illicium religiosum which he had taken. 



Cases 2 and 3 were Mr. and Mrs. B., who one afternoon took 

 an infusion of Illicium religiosum. Mrs. B. drank a smaller 

 portion of the poison. She had early vomiting and profuse 

 diarrhoea. Vomiting did not appear in Mr. B. until one hour 

 later, and the vomitus was less abundant. They developed con- 

 vulsions resembling those described in the case of Mr. 0. Mrs. 

 B. recovered, but her husband, in addition to the convulsions, 

 suffered from anuria, hallucination with tendency to commit 

 violence, and marked paresis of the lower limbs. On the third 

 day he showed considerable improvement, but afterward, anuria, 

 restlessness, insomnia alternating with depression, cyanosis, cold 

 extremities, and oedema in the calf muscles manifested them- 

 selves, and on the eighth day the patient died of asphyxia. 

 Post-mortem examination revealed congestion of the alimentary 

 tract and enlarged, congested kidneys. 



Geerts(6) reported six cases of poisoning by Illicium religio- 

 sum. These cases occurred in Kanagawa, near Yokohama, 

 Japan, and resulted from the substitution of the sesame oil by 

 the fixed oil of Illicium religiosum, in the preparation of food. 

 In one of these cases death occurred. Other cases of poisoning 

 arising from the substitution of Illicium religiosum for Illicium 

 anisatum have also been reported by Planchon and Dreyer,(7) 

 Vogl,(8) Barral,(9) Delotte,(iO) and Lamarque.(li) 



In addition to these cases Eykman mentioned some cases of 

 poisoning which took place at Leeuwarden in the Netherlands, 

 which were caused by fruits which corresponded in botanical 

 description and pharmacological action to the fruits of Illicium, 

 religiosum. He further mentioned five cases of poisoning in 

 five children at Uyeno Park, Tokyo. These children were found 

 playing at the park, foaming at the mouth and violently con- 

 vulsed. The opinion that these were cases of poisoning by 

 Illicium religiosum was based upon the occurrence of a number 

 of fruit-bearing specimens of the plant in Uyeno Park in the 

 neighborhood of the place where the children were playing and 

 the discovery of some seeds of Illicium religiosum in the sleeves 

 of the dresses, -in the vomitus of one child, and in the faeces 



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