x,B1 DuMez: Emetine in Treatment of Entamcebiasis ret 
TABLE II.—The composition of emetine mercuric iodide. 

Found. 






| 
Caleulated for 
Constituent. 4 (CsoH4oN205) Tease Tania metean, | 
(10HD (Hegle)s. 1 9 
| Per cent.| Per cent.| Per cent. | Per cent. 
NCoyo Wh aX Sy pe oe ee Aled ee MANNE oath Oe os sina ns reall a 2, 014. 40 43,43 43. 13 43. 03 43.08 
ING) OTe a phn tee A a ae SL en A ee St Pe oe ae ee | 595.50 12. 84 12.53 12.48 12.50 
15 RG) iNT 2 fb eae Lepr Pea cave att ee ee oe 10. 00 (0) 728) Oa eR a Fe 0.23 
IMIG DIT CR sp Ne oh eee Rs Doe ai | 2,018. 24 ASU On| eens uees Deere aed Sake) 
| 4,638.14 | 100.00 | 100. 90 


Emetine mercuric iodide is a light-yellow powder without 
odor or taste; it is practically insoluble in water or water acid- 
ulated with hydrochloric acid. It is apparently quite stable 
with respect to ordinary physical conditions, as a specimen kept 
in a cork-stoppered bottle for more than four months has under- 
gone no noticeable change. 
EMETINE: BISMUTHOUS IODIDE 
The procedure in the preparation of emetine bismuthous iodide 
was similar in all respects to that followed in the preparation 
of emetine mercuric iodide, except that Dragendorft’s * instead 
of Mayer’s reagent was employed in forming the precipitate. 
Here, also, the composition of the precipitate was found to 
vary with the concentration of the solution. The following 
analytical results '* were obtained for the precipitate formed 
in the dilution of 1 to 300. 
Emetine bismuthous iodide is a brick-red powder, insoluble 
in water or water acidulated with hydrochloric acid. it is quite 
stable in the air. 
“ Dragendorfi’s reagent was prepared by saturating a hot concentrated 
solution of potassium iodide with bismuthous iodide (Bil:), and then dilut- 
ing with an equal volume of a saturated solution of potassium iodide. 
Zeitschr. f. anal. Chem. (1866), 5, 407. 
“The analysis of the bismuth compound was carried out in a manner 
very similiar to that of the mercury precipitate, except that the solution 
was at all times kept rather strongly acid to prevent the formation of basic 
compounds. The filtrate after the removal of the silver as chloride was 
concentrated by evaporation on a water bath and then diluted with water 
containing acetic acid, after which the bismuth was precipitated as sul- 
phide, washed with water containing H.S, dried at 100° C., and weighed. 
The lowest of several weighings taken at intervals of a half-hour was 
the figure used in the computations. 
