X, B, 2 Barber: Experiments on Immunization 153 
TABLE 1V.—Controls of series 1, 2, and 3. 











i: . 
=| Aug.6, | Sept. 23,| Nov. 16, | Dec. 19, | Apr. 14, a Autopsy. 
| 1912; 61 | 1912;110 | 1912; 164 | 1912; 197 | 1918; 3138] 3 HA Sib eaeraen 
aS days after |days after| days after | days after | days af- 2 ae 
virulent | virulent |} virulent virulent |ter viru- oO ou 
= anal Tl aC ay A ! 
egies dose. dose. dose. dose. |lentdose.| ‘5 2 
© oN ‘7 : fay 
ee toa =e weve 2] Pall 
to pes |e =. = = = e a) =) | 
S Petal Sa kt Sal lh Sia oe Sal te SRI elie 9 alata . | Os 
e (egies e fest ees | Seo ees es ae | Eig | a) ae | 
2 |35|28| @(28| @| es] me] 28] @ les | o |e] 8 | & | ges 
5/83] *a| S ) a) © | we! ol ee] S eae] S| 8) S| e | eee 
S |SehE eles | ele Pelee] Ss ye] wa | se 
3 us = : 2 = i aah AER = 
g. > ae g g. g g. |Days.| g. g. 
6252 | 480 ae 500; + | 580 aF 550 + 610 | + | 630 j512 670 | 2.8 Tb. |0.0057 
6253 | 480 | + 540 |} + | 590 ar 540 a 590 | + | 550 361 470 | 1.7 Tb. \0.0036 
6254 | 480 Se AOD) Jl se aay pee ee lemaser aan See esa 159 ' 400 | 2.6 Tb. |0.0065 
6255 | 610 + 600 | + | 650 ar 600 + | 640 | + | 630 |460 440 | 1.8 Tb. ,0.0041 
6256 | 590 Se |) GEO Srey) NK) an 540 ar 580 | + | 465 \465 560 | 1.9 Tb. |0.0035 
6257 | 500 AF 550 | + | 560 ar 520 ar 540 | + | 600 497 450 | 1.0 Tb. 0.0022 
sts |) SEO ap 2 Se ) AAD Wessel oe ele satel bop dyed |132 390 | 8.7 Tb. jC. 0223 
62598430) eat e=s (ese ee SPE, cd ie Ped re Pl Balai leeciel ee eee 33110) jee (@) ekeSsesss 
| 
6260 | 600 ar 600 | ++] 620 | ++ | 550! ++ | 480 |____|_____ 202 460 | 3.1 Th. |0. 0067 
6261 | 580 | ++ | 570] + | 600 + 670 oF 600 | + | 650 482 500 | 7.5 Tb. |0.0150 | 
6262 | 540) + LOT ete ROOM nee | Se eee Pa ae Bea ae 136 450 | 8.2 Tb. |0.0182 
ER 200 ea eee Pc eo eb ee el Shae (eee 21 cent | (Oss eee 
BOY [ies tops ke So ee ls | wo ie ela | ee tees 5.4 0.065) | ee (BOB |eeece 0. 0088 

















8 Intercurrent disease. 
virulent dose, it is noteworthy that avian 6078, series 2, Table II, 
survived the virulent dose eight hundred twelve days, or over 
two years and two months, and that avian 5983 survived eight 
hundred forty-two days, or over two years and three months. 
However, if we take the series as a whole, we find that the 
average number of days of survival of the controls (Table IV) 
is higher than that of any series of treated animals. 
These averages, compared with the controls, are as follows: 
TABLE V.—Average survival of treated and of control guinea pigs. 







vee Aver- 
“in ni- age 
Series. Table. ae a ea 
vival. 
4 | Days. 
(ie eee eee & I 9 | 236.6 
QEe ae eer | II 25 | 308.8 
Shae fle aes ) II 11 | 292.9 
Controls _---- IV 10 | 340.6 

A few animals died of plague of rat-flea origin. These and the 
animals which died of any other intercurrent disease are re- 
