x, B, 6 Coulter: Gall Bladder and Biliary Passages in Cholera 889 
no round-cell infiltration. These changes were only in the gall 
bladder; the other four sections of this case showed no changes. 
The sections were all stained specially for the cholera vibrio 
with carbol fuchsin and Léffler’s methylene blue, with negative 
results. 
In the autopsies of cases in 1913-14 that were examined in the 
pathological laboratory of the College of Medicine and Surgery, 
University of the Philippines, the histological sections of the 
gall bladders were available for examination. By specially 
staining the sections for bacteria with carbol fuchsin, comma 
bacilli were demonstrated in two cases (autopsy Nos. 3557 and 
8751). These were in all probability the cholera vibrio, but 
Grieg, (18) in a recent paper, cautions against error in diagnosis 
between the cholera vibrio and choleralike vibrio. These comma 
bacilli were in the mucosa and submucosa, and many resembled 
the involution form mentioned by Kulescha. The sections showed 
desquamation of the epithelial layer of the mucosa and round-cell 
infiltration, but no such marked changes as were recorded by 
Kulescha. In the cases of 1913-14 the pathological changes 
were not so marked as seen by Kulescha in many of his cases, 
but showed a catarrhal inflammation. The percentage, 4, is the 
same as that recorded by Grieg. 
REFERENCES 
(1) KutescHa. Klin. Jahrb. (1910), 24, 1387. 
(2) Prrocorr. Die Pathologische Anatomie der Cholera, St. Petersburg 
(1850). 
(3) NetscHArEFF. Bolnicenaja Gazeta Botkina (1892). 
(4) Nicati, W., and RietscH, M. Arch. physiol. norm. et path. (1885), 
JUN, WGp We 
(5) DoyEeN, E. Ibid. (1885), III, 16, 179. 
(6) KeuscH, A., and VAILLARD, L. Ibid. (1885), III, 15, 341. 
(7) Tizzoni, G., and CATTANI, J. Centralbl. f. med. Wissensch. (1886), 
24, 769. 
(8) RAPTSCHEVSKY, J. F. Russkyi Vratch (1886), No. 4, 5. 
(9) ReExKovsky, L. P. Arch. sci. biol., St. Petersbourg (1892). 
(10) DEFRESSINE, C., and CAZENEUVE, H. Compt rend. Soc. biol. (1912), 
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(11) SawTscHENKO. Russkyi Vratch (1893), No. 21. 
(12) GiropE, M. J. Compt. rend. Soc. biol. (1893), 5, 568, 570. 
(18) BRuULLOFF. Russkyi Vratch (1910), 9, 1821. 
(14) Grizec. Ind. Journ. Med. Res. (1918), 1, 44. 
(15) Ipem. Lancet (1912), 2, 1423. 
(16) Ipem. Ind. Journ. Med. Res. (1914), 2, 28. 
(17) ScH6si, O. Phil. Journ. Sci., Sec. B (1915), 10, 11. 
(18) Grieg. Ind. Journ. Med. Res. (1914), 2, 604. 
186701—3 
