﻿46 The Philippine Journal of Science 1914 



purposes on August ^5, 1911, having come from Davao District, 

 Mindanao. It was kept in quarantine with the other experi- 

 mental animals until inoculated on September 23, 1911. At that 

 time this animal and bull 3205 were each given 10 cubic centi- 

 meters of virulent blood from an animal sick with rinderpest. 



Nine days after inoculation, 3235 was noticed to have a diar- 

 rhoea and the eyes were slightly congested; at ten days the 

 diarrhoea became profuse, seropurulent exudate was discharged 

 from the eyes and nostrils, and the animal ate but little. After 

 eleven days the animal stopped eating and displayed all the 

 external appearances of a severe case of rinderpest, except that 

 the temperature had not at any time gone higher than 38°. 9 C. 

 On the twelfth day the temperature dropped to 36°.4 C, which 

 is subnormal, and the animal died during the night of the twelfth 

 day after inoculation. Post-mortem examination revealed large 

 ulcers in the mouth and marked congestion of the peritoneal 

 cavity, fourth stomach, and rectum. The duodenum was also 

 markedly congested, and showed many small ulcers. The csecum 

 was but slightly congested excepting around the ileocaecal valve. 

 Thus the lesions were regarded as typical of those of rinderpest. 



From the temperature chart of 3235 it can be noted that the 

 temperature never rose above normal and was a little lower than 

 that of the average healthy animal. On the fifth and sixth day 

 there was a variation in the temperature which is often seen 

 in rinderpest just before the initial rise. However, the only 

 typical evidence of rinderpest so far as temperature is concerned 

 was the drop to subnormal on the eleventh day, at the time of 

 collapse. 



There is no doubt that animal 3235 was suffering from rin- 

 derpest, for 3205, which was inoculated with the same blood, 

 experienced a typical attack. The identity of the disease in 

 3235 is further shown by a series of inoculations of its blood, 

 at various stages of the attack, into other animals. Susce,ptible 

 animals were inoculated with blood at three, four, five, six, and 

 eleven days after the original inoculation of 3235. Of these, 

 5 animals contracted typical attacks of rinderpest and 3 died, 

 and post-mortem examination showed typical lesions of rinder- 

 pest. No injections were made from the seventh to tenth days 

 after injection because at that time the absence of the febrile 

 temperature in 3235 led to the conclusion that the animal did 

 not have rinderpest. Susceptible animals were exposed in the 

 same pen with 3235 on the eleventh and twelfth days without 

 contracting rinderpest. Another susceptible animal was exposed 

 for twenty-four hours in the same pen in which 3235 had died 



