﻿100 ^^^ Philippine Journal of Science 1914 



Two of the emetine cases which were discharged while still 

 positive for entamoebse quickly reentered the hospital with re- 

 lapses. One of the two ipecac cases which were discharged 

 unimproved was in the hospital a fraction less than five days. 

 Five of the ten laboratory examinations made in the other case 

 were negative. A culture was negative for dysentery bacilli 

 in this case, but it is considered very probable that entamoebse 

 were not entirely responsible for the dysenteric symptoms. 



The results obtained in our dysenteric cases are compared in 

 Table VII with those secured by Rogers(5). It is to be noted 

 that his results are more in favor of emetine, as contrasted with 

 ipecac, than our own and that we secured better results than he 

 did with ipecac. 



NONDYSENTERIC CASES 



By actual occurrence and by estimation, two consecutive final 

 negative examinations were present in the several series of 

 nondysenteric cases as follows (see Table VIII). 



Per cent. 

 Control cases 11 25.0 



Ipecac cases 24 70.6 



Emetine cases 7 36.8 



Neosalvarsan cases 8 100.0 



It would appear from the foregoing that 25 per cent of the 

 cases apparently "cured" by ipecac, emetine, and neosalvarsan 

 would have given two consecutive final negative examinations 

 without treatment and hence that this percentage should be 

 subtracted from cases "cured" by medication. Two factors 

 are to be considered at this point, however; namely, (1) the 

 number of examinations made of control cases which were 

 constantly positive and (2) the average number of days from 

 the beginning of observation of controls as compared with that 

 from the commencement of treatment of the other cases to the 

 first of the two final negatives. Table IV shows that 11, or 

 61.1 per cent, of the 18 controls which were constantly positive 

 were examined only twice. It is highly probable that some of 

 these cases would have yielded one or more negatives if more 

 examinations had been made of each case. Accordingly, 25 + 

 per cent of the controls may be considered as having given two 

 consecutive final negative examinations. The average number of 

 days from the beginning of observation of controls as compared 

 with that from the beginning of treatment of the other cases 

 to the first of the two final negatives was — 



