﻿172 The Philippme Journal of Science 1914 



from the presence of malarial parasites, was of little aid in diag- 

 nosing malaria under the conditions existing in this investigation. 

 Only in the minority of cases in which there was a large increase 

 of the large mononuclear leucocytes and in the extremely few 

 cases in which leucocytes containing malarial pigment were 

 found was the blood picture significant. 



Thomson (5) has shown that there exists a considerable fluc- 

 tuation in the leucocyte counts made at different stages of 

 malarial infection. These fluctuations fnclude a decrease in the 

 total leucocytes in the peripheral blood during active malaria, 

 varying more or less inversely with the temperature ; an inverse 

 relation between the number of mononuclear leucocytes and the 

 temperature; and transient periodic leucocytosis, chiefly of the 

 polymorphonuclear leucocytes, in latent malaria. These fluctua- 

 tions would probably explain some of the variable differential 

 leucocyte counts obtained in these cases. 



The increase in the proportion of the eosinophile leucocytes 

 found in a large number of these cases was probably due for 

 the most part to intestinal parasites with which these persons 

 were infected. 



That so many apparently well adults show malaria parasites 

 in their blood in the dry season when mosquitoes have been re- 

 duced to a minimum indicates a serious malarial problem for 

 the promoters of the San Jose Estate; and the facts that the 

 population of this estate is an imported one and that it is esti- 

 mated that 90 per cent of the individuals remain for less than six 

 months at San Jose and then return to their homes in various 

 parts of the Archipelago constitute a grave public-health problem 

 for the whole Philippines. This estate may be considered as a 

 center of infection to which nonimmune persons are constantly 

 coming and from which a constant stream of infected persons 

 are going out to all parts of the Philippines. Since the mosquito 

 that is incriminated in the transmission of malaria in these 

 Islands is of wide distribution, these emigrating cases must 

 serve as foci of infection in various parts of the Philippine 

 Islands. 



THE MICROSCOPIC EXAMINATION OF F^CES FOR INTESTINAL 



PARASITES 



The 58 stool examinations made were all of adult males. The 

 results of these examinations are shown in Table VI. 



