﻿IX, B, 3 Boynton: Kidney-worm Infestation of Swine 277 



2, b). The nuclei retained their staining power remarkably, as 

 will be noticed in Plate II, fig. 3, d. Although the cell body had 

 become completely broken up into droplets, the nucleus stained 

 almost as perfectly as in a healthy cell. The nuclei did not 

 become destroyed until after they had flowed into the lumen of 

 the tubule. 



All the parenchymatous tissue was not affected in this manner. 

 The degeneration occurred in areas, involving from 4 to 8 or 

 more tubules, and was more prominent in the cortex than in the 

 medulla. Frequently, there were accumulations of round cells 

 which had the appearance of lymphoid tissue and took the 

 heematoxylin stain deeply. These cells were either scattered 

 through, or were in the immediate vicinity of, the degenerating 

 areas. 



An occasional glomerulus was found, in which the space be- 

 tween the outer and inner capsule was filled with homogeneous 

 colloid-appearing material. As the glomerular tissue and cap- 

 sule showed no apparent degeneration, this colloid material must 

 have been forced into the cavity through the constricted neck 

 of the convoluted tubules. The marked passive congestion was 

 undoubtedly instrumental in the retrogade fiow of this material. 



Sections made from the kidney represented in Plate I, fig. 4, 

 showed that there was practically a complete destruction of the 

 parenchymatous tissue in both the cortex and medulla. The 

 lining connective tissue framework of the tubules could be seen 

 practically denuded of parenchymatous tissue. The spaces were 

 either empty or filled with cell detritus mixed with a faintly 

 staining, colloidlike substance, which showed complete destruc- 

 tion of the functional tissue in that particular specimen. 



LIVER 



The most striking appearance in the liver on microscopical 

 examination was the marked passive congestion present. This 

 varied in degree in diflferent portions of the organ. 



As a rule, sections made from the upper portions of the lobe 

 showed the portal vein to be distended with blood, practically 

 all the interlobular capillaries were congested, and the central 

 vein was distended. The liver cells generally showed slight 

 parenchymatous degeneration. In the interstitial tissue, there 

 was usually an abnormal number of leucocytes present, especially 

 small lymphocytes, and to a lesser extent eosinophiles. Leuco- 

 cytes were also seen in the interlobular capillaries, working 

 their way through the capillary walls and invading the individual 

 liver cells. 



