﻿280 The Philippine Journal of Science 1914 



which in most cases held their closely packed appearance. The 

 medulla was likewise markedly congested, and in some instances 

 hsemorrhagic. 



The next stage showed a thickening of the capsule and 

 trabeculse, with pronounced congestion, haemorrhages, and even 

 necrosis of the follicular substance. Thrombi were frequently 

 found in the blood vessels. In Plate II, fig. 4, c, is shown a 

 large thrombus in an artery located in the trabeculae. This 

 particular thrombus had almost occluded the vessel, and was of 

 the mixed type. The vessel walls, b, and the trabeculae, d, were 

 thickened. 



In some of the glands thus affected, one or more worms were 

 embedded in the capsule, passing down into the connective tissue 

 of the trabeculae. 



As the infestation persists, the worms work their way into 

 the substance of the gland. They cause an irritation which 

 brings on an active inflammation, resulting in the formation of 

 a connective tissue capsule around the worm tract. In the 

 course of time, the entire glandular substance is replaced by 

 connective tissue, and the refuse is left by the worm. A section 

 from the lymph gland is represented in Plate III, fig. 1, in 

 which practically all the glandular substance has been replaced 

 by worm tracts and fibrous connective tissue. 



Worms were found repeatedly in the glands. They were 

 surrounded by leucocytes, most of which were small lymphocytes 

 intermixed with cell detritus and fibrin. The tract wall was 

 made up of proliferating connective tissue which contained 

 numerous new-forming blood vessels, both single and ramified. 

 Large numbers of round cells and eosinophils were scattered 

 throughout the proliferating connective tissue, and were especially 

 abundant in the borders of the tissue next to the worm. 



A tract apparently occupied by a worm is shown in Plate 

 III, fig. 1, a. It is composed of fibrin, degenerated cells, and 

 small round cells. This tract is surrounded by a connective 

 tissue capsule, b, which contains a large number of new-forming 

 and ramified blood vessels, c. These vessels are practically all 

 distended with blood. A large number of leucocytes and 

 eosinophiles are scattered throughout the connective tissue. A 

 worm tract which is of longer standing than the one shown in 

 Plate III, fig. 1, a, is represented in Plate III, fig. 1, d. The 

 contents of this tract are made up of fibrin, cell detritus, and 

 leucocytes. There is a layer immediately around this (fig. 1, e) 

 which takes a pinkish red stain with eosin, which suggests 



